Overview
- Editors:
-
-
M.A. Hayat
-
, Kean University, Room 213, Library building, Union, USA
- Personalizing cancer care
- Role of MicroRNA in distinguishing tumors
- Genomic analysis of glioblastoma
- Imaging to study brain cancer
- Miolecular profiling of brain tumors
Access this book
Other ways to access
Table of contents (36 chapters)
-
Front Matter
Pages i-xxvi
-
Introduction
-
-
- Isabelle Baldi, Hugues Loiseau
Pages 3-13
-
- Mohit Singh, Juliette Hukin
Pages 15-24
-
- Roberto Gaggero, Alessandro Consales, Francesca Fazzini, Maria Luisa Garrè, Pasquale Striano
Pages 25-31
-
-
Tumor To Tumor
-
- Marc R. Matrana, Nuhad K. Ibrahim
Pages 35-49
-
-
-
Biomarkers And Diagnosis
-
- Luciana Oliveira de Almeida
Pages 59-69
-
-
- Matthew L. Dashnaw, Kevin A. Walter, Eleanor B. Carson-Walter
Pages 79-86
-
- Yongping You, Ning Liu, Chunsheng Kang, Peiyu Pu, Zhen Fu
Pages 87-93
-
- Tan Boon Toh, Yuk Kien Chong, Beng Ti Ang, Carol Tang
Pages 95-101
-
- Filippo Alongi, Arturo Chiti, Pierina Navarria, Marta Scorsetti
Pages 103-110
-
- Robert Pichler, Sabine Spiegl-Kreinecker, Gabriele Wurm
Pages 111-117
-
- B. Mark Woerner, Joshua B. Rubin
Pages 119-127
-
Imaging
-
Front Matter
Pages 129-129
-
- Abedelnasser Abulrob, Umar Iqbal, Boguslaw Tomanek, Danica Stanimirovic
Pages 131-141
-
- Rubén Cárdenes, Emma Muñoz-Moreno, Rosario Sarabia-Herrero, Daniel Argibay-Quiñones, Marcos Martín-Fernández
Pages 143-152
About this book
This volume mainly contains information on the diagnosis, therapy, and prognosis of brain tumors. Insights on the understanding of molecular pathways involved in tumor biology are explained, which should lead to the development of effective drugs. Information on pathways (e.g., hedgehog) facilitates targeted therapies in cancer. Tumor models are also presented, which utilize expression data, pathway sensitivity, and genetic abnormalities, representing targets in cancer. For example, rat model of malignant brain tumors using implantation of doxorubicin with drug eluting beads for delivery is explained. The future of pathway-driven therapies for tumors is summarized. The importance of personalizing cancer care is emphasized. The need for supportive measures for survivors of brain cancer is pointed out, so is the quality of life monitoring. The need of rehabilitation therapy for patients with primary and metastatic brain tumors is also emphasized. Role of MicroRNA in distinguishing primary tumors from metastatic primary tumors is discussed. Advantages and limitations of chemotherapy (e.g., temozolomide and doxorubicin) are discussed. The complexity of tumor to tumor transfer is explained; examples discussed are: brain metastases from breast cancer and brain metastases fro non-small cell lung carcinoma. Identification and characterization of biomarkers, including those for metastatic brain tumors, are presented. Genomic analysis for identifying clinically relevant subtypes of glioblastoma is included. A large number of imaging modalities are detailed to study progression and invasion of gliomas
Reviews
From the reviews:
“The purpose is to address the main achievements in the neuroscience of tumors of the central nervous system. This volume deals with intracranial tumors. Neurosurgeons, neurologists, neuroradiologists, neuropathologists, molecular biologists, radiation therapists, and radiologists are the main audience. … The illustrations, text, and presentation are superb. Excellent in its presentation, content, and up-to-date information, this book deserves a spot in academic libraries serving neurosurgeons and neurologists.” (Celso Agner, Doody’s Review Service, March, 2012)
Editors and Affiliations
-
, Kean University, Room 213, Library building, Union, USA
M.A. Hayat