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  • © 2015

Tumor Cell Metabolism

Pathways, Regulation and Biology

  • Gives a clear overview of novel aspects in tumor cell metabolism

  • Maps and explains signaling pathways of tumor metabolome biology

  • Written by international experts

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-viii
  2. On the Roles of Altered Tumor Cell Metabolism in Tumor Biology

    1. Front Matter

      Pages 1-1
    2. Metabolic Remodeling in Bioenergetic Disorders and Cancer

      • Emilie Obre, Rodrigue Rossignol
      Pages 3-22
    3. Autophagy and Tumor Cell Metabolism

      • Ahmed Hamaï, Joelle Botti, Maryam Mehrpour, Patrice Codogno
      Pages 45-63
  3. Some Specific Regulators of Cellular Metabolism in Normal and Cancer Cells

    1. Front Matter

      Pages 99-99
    2. MYC Regulation of Metabolism and Cancer

      • Arvin M. Gouw, Annie L. Hsieh, Zachary E. Stine, Chi V. Dang
      Pages 101-122
    3. Pyruvate Kinase M2: A Metabolic Tuner

      • Vibhor Gupta, Mohd Askandar Iqbal, Bhupender Kumar, Rameshwar N. K. Bamezai
      Pages 123-142
    4. Role of the Pentose Phosphate Pathway in Tumour Metabolism

      • Adrián Benito, Santiago Diaz-Moralli, Johannes F. Coy, Josep J. Centelles, Marta Cascante
      Pages 143-163
    5. Contribution of pH Alterations to the Tumor Microenvironment

      • Angela Strambi, Angelo De Milito
      Pages 173-196
  4. On the Role of Mitochondria in Tumor Metabolism

    1. Front Matter

      Pages 197-197
    2. Mitochondrial Mutations in Cancer Progression: Causative, Bystanders, or Modifiers of Tumorigenesis?

      • Ivana Kurelac, Michele Vidone, Giulia Girolimetti, Claudia Calabrese, Giuseppe Gasparre
      Pages 199-231
    3. The Relevance of the Mitochondrial H+-ATP Synthase in Cancer Biology

      • Inmaculada Martínez-Reyes, José M. Cuezva
      Pages 233-256
    4. Canceromics Studies Unravel Tumor’s Glutamine Addiction After Metabolic Reprogramming

      • Javier Márquez, José M. Matés, Francisco J. Alonso, Mercedes Martín-Rufián, Carolina Lobo, José A. Campos-Sandoval
      Pages 257-286
    5. Essential Role of Mitochondria in Pyrimidine Metabolism

      • Monika Löffler, Elizabeth A. Carrey, Elke Zameitat
      Pages 287-311
  5. On the New Omics of Metabolism

    1. Front Matter

      Pages 313-313
    2. Metabolic Fluxes in Cancer Metabolism

      • Ulrich L. Günther, Mei G. Chong, Tatiana Volpari, Katarzyna M. Koczula, Karen Atkins, Christopher M. Bunce et al.
      Pages 315-348
    3. Targeted 13C-Labeled Tracer Fate Associations for Drug Efficacy Testing in Cancer

      • László G. Boros, Richard D. Beger, Emmanuelle J. Meuillet, Jerry R. Colca, Sándor Szalma, Patricia A. Thompson et al.
      Pages 349-372

About this book

The four sections of this book cover cell and molecular biology of tumor metabolism, metabolites, tumor microenvironment, diagnostics and epigenetics. Written by international experts, it provides a thorough insight into and understanding of tumor cell metabolism and its role in tumor biology. The book is intended for scientists in cancer cell and molecular biology, scientists in drug and diagnostic development, as well as for clinicians and oncologists.

Editors and Affiliations

  • Inst. of Veterinary Physiology and Bioch, Justus-Liebig-University of Giessen, Gießen, Germany

    Sybille Mazurek

  • Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden

    Maria Shoshan

Bibliographic Information

  • Book Title: Tumor Cell Metabolism

  • Book Subtitle: Pathways, Regulation and Biology

  • Editors: Sybille Mazurek, Maria Shoshan

  • DOI: https://doi.org/10.1007/978-3-7091-1824-5

  • Publisher: Springer Vienna

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer-Verlag Wien 2015

  • Hardcover ISBN: 978-3-7091-1823-8Published: 29 January 2015

  • Softcover ISBN: 978-3-7091-1989-1Published: 06 October 2016

  • eBook ISBN: 978-3-7091-1824-5Published: 19 January 2015

  • Edition Number: 1

  • Number of Pages: VIII, 374

  • Number of Illustrations: 17 b/w illustrations, 35 illustrations in colour

  • Topics: Cancer Research, Molecular Medicine, Oncology

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access