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Oncogenes and Growth Control

  • Book
  • © 1986

Overview

Editors:
  1. Patricia Kahn

    1. European Molecular Biology Laboratory, Heidelberg, Germany

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    You can also search for this editor in PubMed   Google Scholar

  2. Thomas Graf

    1. European Molecular Biology Laboratory, Heidelberg, Germany

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    You can also search for this editor in PubMed   Google Scholar

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Table of contents (48 chapters)

  1. Front Matter

    Pages I-XXIII
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  2. Introduction

    1. Introduction

      • Patricia Kahn, Thomas Graf
      Pages 1-5

  3. Growth Factors and Proto-Oncogenes in Development and Differentiation

    1. Front Matter

      Pages 7-8
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    2. The Expression of Growth Factors and Growth Factor Receptors During Mouse Embryogenesis

      • Aya Jakobovits
      Pages 9-17

    3. A Role for Proto-Oncogenes in Differentiation?

      • Erwin F. Wagner, Rolf Müller
      Pages 18-26

    4. Tissue-Specific Expression and Possible Functions of pp60c-src

      • Larry R. Rohrschneider
      Pages 27-31

  4. Growth Factors, Receptors, and Related Oncogenes

    1. Front Matter

      Pages 33-34
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    2. The Granulocyte-Macrophage Colony-Stimulating Factors

      • Nicholas M. Gough
      Pages 35-42

    3. Role of PDGF-Like Growth Factors in Autocrine Stimulation of Growth of Normal and Transformed Cells

      • Carl-Henrik Heldin, Bengt Westermark
      Pages 43-50

    4. Transforming Growth Factor-β

      • Harold L. Moses, Edward B. Leof
      Pages 51-57

    5. Transforming Growth Factor-α

      • Rik Derynck
      Pages 58-64

    6. The Physiology of Epidermal Growth Factor

      • Graham Carpenter, Linda Goodman, Lynn Shaver
      Pages 65-69

    7. Structural Relationships Between Growth Factor Precursors and Cell Surface Receptors

      • Suzanne Pfeffer, Axel Ullrich
      Pages 70-76

    8. Regulation of Cell Growth by the EGF Receptor

      • Joseph Schlessinger
      Pages 77-84

    9. Mutational Analysis of v-erbB Oncogene Function

      • Hartmut Beug, Michael J. Hayman, Björn Vennström
      Pages 85-92

    10. The c-fms Proto-Oncogene and the CSF-1 Receptor

      • Charles J. Sherr, E. Richard Stanley
      Pages 93-99

    11. Activation of the c-src Gene

      • Hidesaburo Hanafusa
      Pages 100-105

    12. Normal and Transforming N-Terminal Variants of c-abl

      • Yinon Ben-Neriah, David Baltimore
      Pages 106-114

    13. Transformation by the v-abl Oncogene

      • Angelika Gebhardt, J. Gordon Foulkes
      Pages 115-120

    14. mos

      • Donald G. Blair
      Pages 121-127
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Keywords

About this book

How is growth controlled in normal cells? How are the growth control mechanisms perturbed in cancer cells? This book provides an up-to-date description of research aimed at resolving these questions. It is organized into four sections, each containing a series of short reviews written by experts in the field. The general headings are: growth factors, receptors, and related oncogenes: transduction of mitogenic signals and ras oncogenes; nuclear oncogenes and regulation of gene expression; and multiple steps involved in malignant transformation. The articles emphasize concepts rather than detailed facts and are intended not only for specialists in the field but also for interested readers, such as physicians and advanced students, who wish to stay abreast of developments in one of the most exciting fields in current biomedical research.

Editors and Affiliations

  • European Molecular Biology Laboratory, Heidelberg, Germany

    Patricia Kahn, Thomas Graf

Bibliographic Information

  • Book Title: Oncogenes and Growth Control

  • Editors: Patricia Kahn, Thomas Graf

  • DOI: https://doi.org/10.1007/978-3-642-73325-3

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1986

  • Softcover ISBN: 978-3-540-18760-8Published: 15 March 1988

  • eBook ISBN: 978-3-642-73325-3Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XXIII, 369

  • Number of Illustrations: 1 b/w illustrations

  • Topics: Cancer Research, Cell Biology, Oncology, Virology, Biochemistry, general

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