Skip to main content
SpringerLink
Log in

Natural Killer T cells

Balancing the Regulation of Tumor Immunity

  • Book
  • © 2012

Overview

Editors:
  1. Masaki Terabe

    1. National Cancer Institute (NCI), Molecular Immunogenetics & Vaccine, National Institutes of Health (NIH), Bethesda, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Jay A. Berzofsky

    1. National Cancer Institute, Lab. Developmental &, National Institutes of Health (NIH), Bethesda, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Natural killer T (NKT) cells discussed in this book are CD1d-restricted T cells
  • Overview of structures and functions of glycolipid antigens
  • Explains roles of NKT cells in human lymphoma patients
  • Includes supplementary material: sn.pub/extras

Part of the book series: Cancer Drug Discovery and Development (CDD&D)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (11 chapters)

  1. Front Matter

    Pages i-xi
    Download chapter PDF

  2. Introduction: Mechanisms of NKT-Cell-Mediated Adjuvant Activity and Function of iPS-Derived NKT Cells

    • Masaru Taniguchi, Shin-ichiro Fujii, Toshinori Nakayama, Shinichiro Motohashi, Nyambayar Dashtsoodol, Hiroshi Watarai et al.
    Pages 1-13

  3. Structure and Recognition of Antigens for Invariant NKT Cells

    • Bo Pei, Mitchell Kronenberg
    Pages 15-37

  4. Invariant NKT Cell-Based Vaccine Strategies

    • John-Paul Jukes, Jonathan D. Silk, Mariolina Salio, Vincenzo Cerundolo
    Pages 39-53

  5. Immune Regulation of Tumor Immunity by NKT Cells

    • Jessica J. O’Konek, Jay A. Berzofsky, Masaki Terabe
    Pages 55-70

  6. The Regulation of CD1d+ and CD1d− Tumors by NKT Cells

    • Jianyun Liu, Gourapura J. Renukaradhya, Randy R. Brutkiewicz
    Pages 71-94

  7. DC-Based Immunotherapy Targeting NKT Cells

    • Shin-ichiro Fujii, Kanako Shimizu
    Pages 95-110

  8. Therapeutic Approaches Utilising NKT Cells

    • Stephen R. Mattarollo, Mark J. Smyth
    Pages 111-128

  9. NKT Cells of Cancer Patients and How Models Can Inform Therapeutic Plans

    • Mark A. Exley, Lydia Lynch, Michael Nowak
    Pages 129-151

  10. Understanding the Role of Natural Killer T Cells in Hematologic Malignancies: Progress and Challenges

    • Natalia Neparidze, Madhav V. Dhodapkar
    Pages 153-167

  11. Clinical Trials with α-Galactosylceramide (KRN7000) in Advanced Cancer

    • Famke L. Schneiders, Rik J. Scheper, Hetty J. Bontkes, B. Mary E. von Blomberg, Alfons J. M. van den Eertwegh, Tanja D. de Gruijl et al.
    Pages 169-183

  12. Clinical Trials of Invariant Natural Killer T Cell-Based Immunotherapy for Cancer

    • Shinichiro Motohashi, Yoshitaka Okamoto, Toshinori Nakayama
    Pages 185-198

  13. Back Matter

    Pages 199-205
    Download chapter PDF
Back to top

Keywords

About this book

This book will cover primary roles of NKT cells in immunity to cancer, in both mouse tumor models and cancer patients. There are several chapters describing general aspects of NKT cells.

Reviews

From the reviews:

“This book is essentially a collection of reviews that introduce the reader to the wonderful world of iNKT cells, and how their powerful adjuvant properties are being utilised by different researchers. … this book is worth reading whether you are a new student in the NKT field and want to learn more or whether you are a clinician with an interest in tumour immunology.” (Salah Mansour, Immunology News, November, 2012)

Editors and Affiliations

  • National Cancer Institute (NCI), Molecular Immunogenetics & Vaccine, National Institutes of Health (NIH), Bethesda, USA

    Masaki Terabe

  • National Cancer Institute, Lab. Developmental &, National Institutes of Health (NIH), Bethesda, USA

    Jay A. Berzofsky

Bibliographic Information

  • Book Title: Natural Killer T cells

  • Book Subtitle: Balancing the Regulation of Tumor Immunity

  • Editors: Masaki Terabe, Jay A. Berzofsky

  • Series Title: Cancer Drug Discovery and Development

  • DOI: https://doi.org/10.1007/978-1-4614-0613-6

  • Publisher: Humana New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media, LLC 2012

  • Hardcover ISBN: 978-1-4614-0612-9Published: 21 September 2011

  • Softcover ISBN: 978-1-4614-2950-0Published: 25 October 2013

  • eBook ISBN: 978-1-4614-0613-6Published: 22 September 2011

  • Series ISSN: 2196-9906

  • Series E-ISSN: 2196-9914

  • Edition Number: 1

  • Number of Pages: XII, 208

  • Topics: Cancer Research, Pharmacology/Toxicology

Publish with us

Policies and ethics

Back to top

Search

Navigation