2012, XXIII, 866 p. 125 illus., 68 illus. in color.
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This proposed volume will attempt to review and address the major gaps in current knowledge in DNA viruses
This volume will in addition discuss RNA viruses and bring a historical perspective of where studies began to a more recent molecular approach and vaccine successes in tumor viruses
This volume will also cover other known oncogenic viruses associated cancers in other mammals in addition to humans
This volume constitutes a comprehensive review of the different aspects of tumor virology 100 years after the discovery of the Rous-sarcoma virus. Its aim is to bring a greater focus on the contributions of viral agents to the development of cancer, and to create an up to date compendium of the general molecular biology of these viruses, their gene products, and targeted functions. The content of the book comprises general chapters which tie into the many aspects of cancer-related viruses and how they contribute to cell proliferation, the genes that are responsible for driving these cancers, and their mechanisms of transmission. The book also reviews the current knowledge on the molecular biology of large DNA viruses and describes the many different pathways through which they contribute to cell proliferation. Papilloma viruses and Adenoviruses, well known to be associated with invasive carcinomas, and hepatitis viruses, HTLV and retroviruses are also discussed. This volume is dedicated to Baruch Blumberg, an outstanding scientist and recipient of the Nobel Prize for the discovery of the hepatitis B virus, who was also the author of one of the chapters.
1. Historical Perspectives of Viruses and Cancer - Baruch Blumberg
2. Peyton Rous: A centennial tribute to the founding father of cancer virology.
3. Virus Mediated Cell Proliferation - Jae Jung
4. Viral Encoded Genes and Cancer - Blossom Damania
5. Oncogenic Viruses and Cancer Transmission- Robin Weiss
6. Overview of DNA Viruses and Cancer – James Alwine
7. Herpesviruses and Cancer – Bala Chandran
8. Lymphocryptoviruses- EBV and its role in human cancer – Erle S. Robertson
9. LCV and RRV in nonhuman primates – Scott Wong
10. Rhadinoviruses – KSHV and associated malignancies – Thomas Schultz
11. RFHV and contribution to disease –Tim Rose
12. Murine herpesvirus 68 in Tumorigenesis – Sam Speck
13. Marek’s Disease Virus and T cell Lymphomas – Mark Parcells and Robin Morgan
14. Polyoma Viruses and Cancer –Ole Gjoerup
15. SV40 as a Model System for Cancer – Janet Butel
16. BK virus and Transformation – Hans Hirsch
17. JC virus and Transformation –Kamel Khalili
18. Merkel Cell Polyoma viruses – Jurgen Becker
19. Papilloma Viruses – HPV and BPV and Cancer – Jianxin You and Suzanne Wells
20. Adenoviruses and Cell proliferation – Robert Ricciardi
21. Overview of Hepatitis Viruses and Cancer – Tim Block
22. Hepadna Viruses - HBV and Hepatocellular Carcinomas – Bill Mason
23. Hepatitis C Virus and Hepatocellular Carcinomas – Brett Lindenbach
24. Human and Animal Retroviruses: HIV-1 a Risk Factor for Malignancy – Kathleen Boris-Lawrie
25. HTLV-1 and Cell Proliferation – Chou-Zen Giam
26. HTLV-2 and Cell Proliferation – Patrick Green
27. Avian and Murine Retroviruses –Karen Beemon & Naomi Rosenberg
28. Rous Sarcoma Virus –Leslie Parent
29. Mouse Mammary Tumor Viruses – Susan Ross
30. Jaagsiekte Sheep Retrovirus and Lung Cancer – Hung Fan
31. Small RNAs and their Role in Viral Mediated Cancers - Rolf Renne & Sankar Swaminathan
32. Immunodeficiency and Opportunistic Viral infections and Cancer – Charles Wood