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Gene-Based Therapies for Cancer

  • Book
  • © 2010

Overview

Editors:
  1. Jack A. Roth

    1. M.D.Anderson Cancer Center, Dept. Thoracic & Cardiovascular Surgery, University of Texas, Houston, USA

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  • In this volume leading experts have contributed their experience in developing gene therapies for a variety of cancers
  • Translational gene therapy approaches are emphasized
  • Chapters include discussions of specific gene delivery technologies as well as their application to various cancers with extensive discussions of ongoing clinical trials
  • This information should be useful to both students, fellows, and experienced scientists with an interest in this rapidly developing area
  • Includes supplementary material: sn.pub/extras

Part of the book series: Current Cancer Research (CUCR)

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Table of contents (14 chapters)

  1. Front Matter

    Pages i-xiv
    Download chapter PDF

  2. RNAi: A New Paradigm in Cancer Gene Therapy

    • Edna M. Mora, Selanere L. Mangala, Gabriel Lopez-Berestein, Anil K. Sood
    Pages 1-15

  3. Gene-Based Therapy for Cancer: Brain Tumors

    • Hong Jiang, Juan Fueyo
    Pages 17-32

  4. Gene Therapy of Prostate Cancer

    • Svend O. Freytag, Hans Stricker, Benjamin Movsas, Mohamed Elshaikh, Ibrahim Aref, Kenneth Barton et al.
    Pages 33-49

  5. siRNA Versus shRNA for Personalized Cancer Therapy: Mechanisms and Applications

    • John S. Vorhies, Donald D. Rao, Neil Senzer, John Nemunaitis
    Pages 51-62

  6. Tumor Suppressor Gene Therapy

    • Jack A. Roth, John Nemunaitis, Lin Ji, Rajagopal Ramesh
    Pages 63-78

  7. Targeted Oncolytic Adenovirus for Human Cancer Therapy: Gene-Based Therapies for Cancer

    • Toshiyoshi Fujiwara
    Pages 79-93

  8. Gene Therapy for Malignant Pleural Mesothelioma

    • Edmund K. Moon, Sunil Singhal, Andrew R. Haas, Daniel H. Sterman, Steven M. Albelda
    Pages 95-111

  9. Mesenchymal Stem/Stromal Cells as Cellular Vehicles for Tumor Targeting

    • Frank Marini, Matus Studeny, Jennifer Dembinski, Keri L. Watson, Shannon Kidd, Erika Spaeth et al.
    Pages 113-139

  10. Retargeting Adenovirus for Cancer Gene Therapy

    • Erin E. Thacker, David T. Curiel
    Pages 141-153

  11. Lentiviruses: Vectors for Cancer Gene Therapy

    • Yuan Lin, Amar Desai, Stanton L. Gerson
    Pages 155-179

  12. Interleukin-24 Gene Therapy for Melanoma

    • Nancy Poindexter, Rajagopal Ramesh, Suhendan Ekmekcioglu, Julie Ellerhorst, Kevin Kim, Elizabeth A. Grimm
    Pages 181-202

  13. Herpes Simplex Virus 1 for Cancer Therapy

    • Richard L. Price, Balveen Kaur, E. Antonio Chiocca
    Pages 203-230

  14. Telomerase as a Target for Cancer Therapeutics

    • Jerry W. Shay
    Pages 231-249

  15. Gene Therapy for Sarcoma

    • Keila E. Torres, Raphael E. Pollock
    Pages 251-268

  16. Back Matter

    Pages 269-275
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Keywords

About this book

Cancer gene therapy is a novel therapy that targets the underlying genetic defects in the cancer cell. Progress in this field has been rapid and gene therapy promises to further extend personalized cancer treatment. In this volume leading experts have contributed their experience in developing gene therapies for a variety of cancers. Translational gene therapy approaches are emphasized. Chapters include discussions of specific gene delivery technologies as well as their application to various cancers with extensive discussions of ongoing clinical trials. This information should be useful to both students, fellows, and experienced scientists with an interest in this rapidly developing area.

Editors and Affiliations

  • M.D.Anderson Cancer Center, Dept. Thoracic & Cardiovascular Surgery, University of Texas, Houston, USA

    Jack A. Roth

Bibliographic Information

  • Book Title: Gene-Based Therapies for Cancer

  • Editors: Jack A. Roth

  • Series Title: Current Cancer Research

  • DOI: https://doi.org/10.1007/978-1-4419-6102-0

  • Publisher: Springer New York, NY

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Science+Business Media, LLC 2010

  • Hardcover ISBN: 978-1-4419-6101-3Published: 04 August 2010

  • Softcover ISBN: 978-1-4614-2634-9Published: 13 October 2012

  • eBook ISBN: 978-1-4419-6102-0Published: 28 July 2010

  • Series ISSN: 2199-2584

  • Series E-ISSN: 2199-2592

  • Edition Number: 1

  • Number of Pages: XIV, 278

  • Topics: Cancer Research, Pharmacology/Toxicology

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