Overview
- The purpose of this volume is to provide an overview of modern molecular biological approaches to unbiased discovery in cancer research Advances in molecular biology allowing unbiased analysis of changes in cancer initiation and progression will be overviewed These include the strategies employed in modern genomics, gene expression analysis, and proteomics
Part of the book series: Applied Bioinformatics and Biostatistics in Cancer Research (ABB)
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Table of contents (8 chapters)
Keywords
About this book
Molecular biology has rapidly advanced since the discovery of the basic flow of information in life, from DNA to RNA to proteins. While there are several important and interesting exceptions to this general flow of information, the importance of these biological macromolecules in dictating the phenotypic nature of living creatures in health and disease is paramount. In the last one and a half decades, and particularly after the completion of the Human Genome Project, there has been an explosion of technologies that allow the broad characterization of these macromolecules in physiology, and the perturbations to these macromolecules that occur in diseases such as cancer. In this volume, we will explore the modern approaches used to characterize these macromolecules in an unbiased, systematic way. Such technologies are rapidly advancing our knowledge of the coordinated and complicated changes that occur during carcinogenesis, and are providing vital information that, when correctly interpreted by biostatistical/bioinformatics analyses, can be exploited for the prevention, diagnosis, and treatment of human cancers.
The purpose of this volume is to provide an overview of modern molecular biological approaches to unbiased discovery in cancer research. Advances in molecular biology allowing unbiased analysis of changes in cancer initiation and progression will be overviewed. These include the strategies employed in modern genomics, gene expression analysis, and proteomics.
Editors and Affiliations
Bibliographic Information
Book Title: Modern Molecular Biology:
Book Subtitle: Approaches for Unbiased Discovery in Cancer Research
Editors: Srinivasan Yegnasubramanian, William B. Isaacs
Series Title: Applied Bioinformatics and Biostatistics in Cancer Research
DOI: https://doi.org/10.1007/978-0-387-69745-1
Publisher: Springer New York, NY
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Science+Business Media, LLC 2010
Hardcover ISBN: 978-0-387-69744-4Published: 08 September 2010
Softcover ISBN: 978-1-4614-2657-8Published: 05 November 2012
eBook ISBN: 978-0-387-69745-1Published: 02 September 2010
Series ISSN: 2363-9644
Series E-ISSN: 2363-9652
Edition Number: 1
Number of Pages: XII, 192
Topics: Cancer Research, Human Genetics, Laboratory Medicine, Medical Microbiology, Molecular Medicine, Virology