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Biomedical Sciences | Nanomaterial - Impacts on Cell Biology and Medicine


Impacts on Cell Biology and Medicine

Capco, David G., chen, yongsheng (Eds.)

2014, XI, 278 p. 70 illus., 42 illus. in color.

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  • This book gives an intradisciplinary understanding for neophytes as well as establishes investigators
  • Covers a broad field within nanotoxicology, medicine and biology studies
  • Integrates various fields of research
  • Each chapter has a Methodology section which explains how to conduct key technologies

The rapidly developing field of nanomaterials has expanded in many commercial areas.  More recent studies have begun to provide a foundation for understanding how nanomaterials influence cells and how they also can serve as methodological tools for studies in medicine and cell biology, include research into stem cells.  Recent investigations have shown affects of nanomaterials on specific subcellular structures, such as the actin-based brush border network in cells with an increasing emphasis on the barrier function of epithelial tissues.   While other studies have shown involvement of nanoparticles in specific cytoplasmic signal transduction events such as the rise in intracellular free calcium, a signaling event known to regulate many changes in cell architecture and function.    In parallel, nanomaterials are increasingly used in medicine for drug delivery, treatment of cancer, and an increasing number of new applications.   This book investigates these areas and also includes new methods for assessment in cell biology and medicine.

Content Level » Research

Keywords » cell biology - cytotoxicity - drug delivery - epithelial cells - nanomaterials - nanotoxicology - stem cells

Related subjects » Biomedical Sciences - Cell Biology - Characterization & Evaluation of Materials - Engineering - Medicine

Table of contents 

1 Presence in, and release of, nanomaterials from consumer products
 Yu Yang and Paul Westerhoff

2 Nanoparticle aggregation: Principles and modeling
Wen Zhang

3  Influences of nanomaterials on the barrier function of epithelial cells
Shariq Ali and Erik Rytting

4 Engineered nanoparticles induced brush border disruption in a human model of the intestinal epithelium
James J. Faust, Benjamin M. Masserano, Adam H. Mielke, Anup Abraham, and David G. Capco

 5 Nanoparticles: Cellular uptake and cytotoxicity
Isaac  M. Adjei,  Blanka Sharma and Vinod Labhasetwar

6 Atomic force microscopy study of the interaction of DNA and nanoparticles
Kungang LI, Songyan Du, Steven Van Ginkel, and Yongsheng Chen

7 Intracellular signal modulation by nanomaterials
Salik Hussain, Stavros Garantziotis, Fernando Rodrigues-Lima, Jean-Marie Dupret, Armelle Baeza-Squiban, Sonja Boland

8 Nanomaterials: Impacts on cells and cell organelles
Željka Krpetić, Sergio Anguissola, David Garry, Philip Kelly and Kenneth A. Dawson

9 Design, synthesis, and functionalization of nanoparticles for therapeutic drug delivery
Taraka Sai Pavan Grandhi and Kaushal Rege

10 Preparation of nanoscale pulmonary drug delivery formulations by spray drying
Adam Bohr, Christian A. Ruge, and Moritz Beck-Broichsitter

11 Nanomedicine: The Promise and Challenges in Cancer Chemotherapy
Author:  Youssef W. Naguib and Zhengrong Cui

12 Transgenerational effects of NMs
Anna Poma, Sabrina Colafarina,  Gabriella Fontecchio, , and Giuseppe Chichiricco

13 Stem cells and nanomaterials
Maria-Claude Hofmann


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