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Peroxisomes and their Key Role in Cellular Signaling and Metabolism

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  • © 2013

Overview

Editors:
  1. Luis A. del Río

    1. , Depto. Bioquímica, Biología Celular y, Estación Experimental del Zaidín, CSIC, Granada, Spain

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  • Describes the central role played in cellular signaling by peroxisomes from different origins
  • Provides an up-to-date information on the function and metabolism of peroxisomes from human, animal, fungal and plant origin
  • Provides updated information on the metabolic interconnection and cross-talk of peroxisomes with other cell compartments
  • Describes the key cellular function played by peroxisomes as cell generators of important signaling molecules
  • Covers the role played by peroxisomes in human health, aging and disease

Part of the book series: Subcellular Biochemistry (SCBI, volume 69)

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Table of contents (18 chapters)

  1. Front Matter

    Pages i-xii
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  2. Peroxisome Interactions and Cross-Talk with Other Subcellular Compartments in Animal Cells

    • Michael Schrader, Sandra Grille, H. Dariush Fahimi, Markus Islinger
    Pages 1-22

  3. Peroxisomes in Human Health and Disease: Metabolic Pathways, Metabolite Transport, Interplay with Other Organelles and Signal Transduction

    • Ronald J. A. Wanders
    Pages 23-44

  4. Aging, Age-Related Diseases and Peroxisomes

    • Marc Fransen, Marcus Nordgren, Bo Wang, Oksana Apanasets, Paul P. Van Veldhoven
    Pages 45-65

  5. Peroxisomes and the Antiviral Responses of Mammalian Cells

    • Charlotte Odendall, Jonathan C. Kagan
    Pages 67-75

  6. Peroxisome Proliferator-Activated Receptor-α Signaling in Hepatocarcinogenesis

    • Parimal Misra, Navin Viswakarma, Janardan K. Reddy
    Pages 77-99

  7. Involvement of Human Peroxisomes in Biosynthesis and Signaling of Steroid and Peptide Hormones

    • Isabelle Weinhofer, Markus Kunze, Sonja Forss-Petter, Johannes Berger
    Pages 101-110

  8. Peroxisome Ca2+ Homeostasis in Animal and Plant Cells

    • Alex Costa, Ilaria Drago, Michela Zottini, Paola Pizzo, Tullio Pozzan
    Pages 111-133

  9. The Versatility of Peroxisome Function in Filamentous Fungi

    • Ida J. van der Klei, Marten Veenhuis
    Pages 135-152

  10. Essential Roles of Peroxisomally Produced and Metabolized Biomolecules in Regulating Yeast Longevity

    • Adam Beach, Vladimir I. Titorenko
    Pages 153-167

  11. Metabolite Transporters of the Plant Peroxisomal Membrane: Known and Unknown

    • Nicole Linka, Frederica L. Theodoulou
    Pages 169-194

  12. Peroxisomes and Photomorphogenesis

    • Navneet Kaur, Jiying Li, Jianping Hu
    Pages 195-211

  13. Biosynthesis of Vitamin K1 (Phylloquinone) by Plant Peroxisomes and Its Integration into Signaling Molecule Synthesis Pathways

    • Sigrun Reumann
    Pages 213-229

  14. Role of Peroxisomes as a Source of Reactive Oxygen Species (ROS) Signaling Molecules

    • Luisa M. Sandalio, María Rodríguez-Serrano, María C. Romero-Puertas, Luis A. del Río
    Pages 231-255

  15. Peroxisomes as a Source of Auxin Signaling Molecules

    • Gretchen M. Spiess, Bethany K. Zolman
    Pages 257-281

  16. Peroxisomes as Cell Generators of Reactive Nitrogen Species (RNS) Signal Molecules

    • Francisco J. Corpas, Juan B. Barroso, José M. Palma, Luis A. del Río
    Pages 283-298

  17. Role of Plant Peroxisomes in the Production of Jasmonic Acid-Based Signals

    • José León
    Pages 299-313

  18. Role of Plant Peroxisomes in Protection Against Herbivores

    • Mohammed Shabab
    Pages 315-328

  19. Function of Peroxisomes in Plant-Pathogen Interactions

    • Yasuyuki Kubo
    Pages 329-345

  20. Back Matter

    Pages 347-350
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Keywords

About this book

Peroxisomes are a class of ubiquitous and dynamic single membrane-bounded cell organelles, devoid of DNA, with an essentially oxidative type of metabolism. In recent years it has become increasingly clear that peroxisomes are involved in a range of important cellular functions in almost all eukaryotic cells. In higher eukaryotes, including humans, peroxisomes catalyze ether phospholipids biosynthesis, fatty acid alpha-oxidation, glyoxylate detoxification, etc, and in humans peroxisomes are associated with several important genetic diseases. In plants, peroxisomes carry out the fatty acid beta-oxidation, photorespiration, metabolism of ROS, RNS and RSS, photomorphogenesis, biosynthesis of phytohormones, senescence, and defence against pathogens and herbivores. In recent years it has been postulated a possible contribution of peroxisomes to cellular signaling. In this volume an updated view of the capacity and function of peroxisomes from human, animal, fungal and plant origin as cell generators of different signal molecules involved in distinct processes of high physiological importance is presented.

Editors and Affiliations

  • , Depto. Bioquímica, Biología Celular y, Estación Experimental del Zaidín, CSIC, Granada, Spain

    Luis A. del Río

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