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Biomedical Sciences | Regenerative Medicine - From Protocol to Patient

Regenerative Medicine

From Protocol to Patient

Steinhoff, Gustav (Ed.)

2nd ed. 2013, XXI, 1220 p. 159 illus., 80 illus. in color.

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  • Gives a comprehensive overview of the state of the art on the field of regenerative medicine
  • From basic science to cilinical translation and application
  • Knowledge transfer by international leading researchers and clinical specialists of their discipline

The field of regenerative medicine has developed rapidly over the past 20 years with the advent of molecular and cellular techniques. This textbook,  Regenerative Medicine: From Protocol to Patient, aims to explain the scientific knowledge and emerging technology as well as the clinical application in different organ systems and diseases. International leading experts from four continents describe the latest scientific and clinical knowledge of the field of regenerative medicine. The process of translating science of laboratory protocols into therapies is explained in sections on regulatory, ethical and industrial issues.

 

This textbook is organized into five parts: (I) Biology of Tissue Regeneration, (II) Stem Cell Science and Technology, (III) Tissue Engineering, Biomaterials and Nanotechnology, (IV) Regenerative Therapies and (V) Regulation and Ethics.

 

The textbook aims to give the student, the researcher, the health care professional, the physician and the patient a complete survey on the current scientific basis, therapeutic protocols, clinical translation and practiced therapies in regenerative medicine.

Content Level » Graduate

Keywords » Biomaterials - Regenerative medicine - Stem cell research - Stem cell therapy - Tissue Engineering

Related subjects » Biomedical Sciences - Life Sciences - Nanotechnology - Surgery

Table of contents 

Foreword Regenerative Medicine: From Protocol to Patient, Gustav Steinhoff and Hoang Tu-Rapp.- Chapter 1 History of Regenerative Medicine, Raymund E Horch, Laurentiu M Popescu and Elias Polykandriotis.- Part I Biology of Tissue Regeneration.- Chapter 2 Extracellular Matrix and Tissue Regeneration, Yrjö T. Konttinen, Emilia Kaivosoja, Vasily Stegaev, H. Daniel Wagner, Jaakko Levón, Veli-Matti Tiainen and Zygmunt  Mackiewicz.- Chapter 3 Stem Cell Niche, Chenhui Wang, Pei Wen, Pei Sun and Rongwen Xi.- Chapter 4 Stem Cells and Asymmetric Cell Division, Frank Hirth.- Chapter 5 Stem Cells in the Developing and Adult Nervous System, Fumitaka Osakada and Masayo Takahashi.- Part II Stem Cell Science and Technology.- Chapter 6: Characterization and Classification of Stem Cells, Ute Bissels, Dominik Eckardt, Andreas Bosio.- Chapter 7 Human Embryonic Stem Cells, Mikael C.O. Englund, Peter Sartipy and Johan Hyllner.- Chapter 8 Induced Pluripotent Stem Cells, Keisuke Okita, Kazutoshi Takahashi and Shinya Yamanaka.- Chapter 9 Spermatogonial Stem Cells, Ilya Chuykin, Michael Stauske and Kaomei Guan.- Chapter 10 Hematopoietic Stem Cells, Mary Clarke and Jonathan Frampton.- Chapter 11 Cardiovascular Stem Cells, Christoph Brenner, Robert David and Wolfgang-Michael Franz.- Chapter 12 Neural Stem Cells, Yoko Arai, Wieland B. Huttner and Federico Calegari.- Chapter 13 Liver Stem Cells, Tohru Itoh, Hinako Takase, Minoru Tanaka and Atsushi Miyajima.- Chapter 14 Gastrointestinal Stem Cells, M. Sasikala, G.V. Rao, Manu Tandan and D. Nageshwar Reddy.- Chapter 15 Cancer Stem Cells, Murali MS Balla, Anjali P. Kusumbe, Geeta K. Vemuganti and Sharmila A. Bapat.- Chapter 16 Mesenchymal Stem Cells: An Oversimplified Nomenclature for Extremely Heterogeneous Progenitors, Patrick Wuchter, Wolfgang Wagner and Anthony D. Ho.- Chapter 17 Musculoskeletal Stem Cells, Gerben M. van Buul and Gerjo J.V.M. van Osch.- Part III Tissue Engineering, Biomaterials and Nanotechnology.- Chapter 18 When Stemness Meets Engineering: Towards “Niche” Control of Stem Cell Functions for Enhanced Cardiovascular Regeneration, Maurizio Pesce, Giulio Pompilio, Gianluca Polvani and Maurizio C. Capogrossi.- Chapter 19 Vector Technology and Cell Targeting: Peptide-Tagged Adenoviral Vectors as a Powerful Tool for Cell-Specific Targeting, Julia Bäder, Ottmar Herchenröder, Anke Schmidt and Brigitte M. Pützer.- Chapter 20 Regenerative Chimerism Bioengineered through Stem Cell Reprogramming, Timothy J. Nelson, Almudena Martinez-Fernandez, Satsuki Yamada and Andre Terzic.- Chapter 21 Biodegradable Materials, Michael Schroeter, Britt Wildemann and Andreas Lendlein.- Chapter 22 Biomaterials-Enabled Regenerative Medicine in Corneal Applications, Naresh Polisetti, Christopher R. McLaughlin, Geeta K. Vemuganti and May Griffith.- Chapter 23 Functionalized Nanomaterials, Jie Zhou, Wenzhong Li and Changyou Gao.- Chapter 24 Biointerface Technology, Joachim Rychly.- Part IV Regenerative Therapies.- Chapter 25 Emerging Concepts in Myocardial Pharmacoregeneration, Laura C. Zelarayan, Maria Patapia Zafiriou and Wolfram-Hubertus Zimmermann.- Chapter 26 Blood, Michael Schmitt and Mathias Freund.- Chapter 27 Regenerative Medicine in the Central Nervous System: Stem Cell-Based Cell- and Gene-Therapy, Seung U. Kim.- Chapter 28 Regenerative Therapy for Central Nervous System Trauma, Kewal K. Jain.- Chapter 29 Regenerative Therapies for the Ocular Surface, Geeta K Vemuganti, Virender S. Sangwan, Indumathy Marriappan and Dorairajan Balasubramanian.- Chapter 30 Lacrimal Gland Regeneration: Progress and Promise, Shubha Tiwari and Geeta K Vemuganti.- Chapter 31 The Development of a Stem Cell Therapy for Deafness, Nopporn Jongkamonwiwat and Marcelo N. Rivolta.- Chapter 32 Dental, Kristina Arvidson, Michele Cottler-Fox, Solve Hellem and Kamal Mustafa.- Chapter 33 Trachea, Silvia Baiguera and Paolo Macchiarini.- Chapter 34 Lung, Lavinia Iuliana Ionescu and Bernard Thébaud.- Chapter 35 Vascular Regeneration: Endothelial Progenitor Cell Therapy for Ischemic Diseases, Masaaki Ii, Atsuhiko Kawamoto and Takayuki Asahara.- Chapter 36 Heart, Gustav Steinhoff and Bodo Eckehard Strauer.- Chapter 37 Liver, Amar Deep Sharma, Razvan Iacob, Tobias Cantz, Michael P. Manns and Michael Ott.- Chapter 38 Kidney, Sajoscha  Sorrentino and Hermann Haller.- Chapter 39 Gastrointestinal Tract and Endocrine System, Nonsikelelo Mpofu-Mätzig, Michelle Stange, Elmar Jackel, Michael P. Manns and Oliver Bachmann.- Chapter 40 Preclinical Animal Models for Segmental Bone Defect Research and Tissue Engineering, Johannes C. Reichert, A. Berner, Siamak Saifzadeh and Dietmar W. Hutmacher.- Chapter 41 Constraints to Articular Cartilage Regeneration, Georg N. Duda, Joshua O. Eniwumide and Michael Sittinger.- Chapter 42 Muscle and Ligament Regeneration, Thomas Mittlmeier and Ioannis Stratos.- Chapter 43 Skin, Hans-Günther Machens, Christina Irene Günter and Augustinus Bader.- Part V Regulation and Ethics.- Chapter 44 Regulatory Frameworks for Cell and Tissue Based Therapies in Europe and the USA, Gudrun Tiedemann and Sebastian Sethe.- Chapter 45 Ethics and Law in Regenerative Medicine: A Legal and Ethical Outline on Regenerative Medicine in Research in France, Germany and Poland, Greg Becker and Anna Grabinski.

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