Nutrition, Diet and Cancer

1. Front Matter

   Pages i-xv

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2. Aberrant Signaling Pathways in Cancer: Modulation by the Dietary Flavonoid, Quercetin

   • Ramamurthi Vidya Priyadarsini, Siddavaram Nagini

   Pages 1-21

3. Micronutrients and Cancer: Add Spice to Your Life

   • Sahdeo Prasad, Subash C. Gupta, Bharat B. Aggarwal

   Pages 23-48

4. Chemoprevention of Prostate Cancer with Cruciferous Vegetables: Role of Epigenetics

   • Laura M. Beaver, David E. Williams, Roderick H. Dashwood, Emily Ho

   Pages 49-81

5. Molecular Insight and Preclinical Perspective of Thymoquinone as Chemopreventive Agent and Therapeutic Adjunct in Cancer

   • Sanjeev Banerjee, Mansi Parasramka, Fazlul H. Sarkar, Ramzi M. Mohammad

   Pages 83-107

6. Dietary Biofactors in the Management of Cancer: Myth or Reality?

   • Vidushi S. Neergheen-Bhujun, K. S. Kang, O. I. Aruoma, T. Bahorun

   Pages 109-127

7. Nutritional Compounds as Chemopreventive Agents by Proteasome Inhibition

   • Kristin Landis-Piwowar, Elizabeth Smerczak, Jian Zuo, Q. Ping Dou

   Pages 129-148

8. STAT Signaling in Cancer Prevention

   • Su-Ni Tang, Sharmila Shankar, Rakesh K. Srivastava

   Pages 149-167

9. γδ T Cells, Tea and Cancer

   • Jingwei Lu, Vincent J. Pompili, Hiranmoy Das

   Pages 169-184

10. Phytochemical Intakes with a Mediterranean Diet: Levels Achievable with an Exchange List Diet and Potential Biomarkers in Blood

    • Zora Djuric

    Pages 185-208

11. Plant Polyphenols and Their Role in Cancer Prevention and Chemotherapy

    • Sharmila Shankar, Brahma N. Singh, Rakesh K. Srivastava

    Pages 209-234

12. Role of Food Micro-molecules in the Prevention of Cancer

    • Latha Sabikhi, Alok Jha, Sudhir Kumar Tomer, Ashish Kumar Singh

    Pages 235-253

13. The Protective Role of Zinc in Cancer: A Potential Chemopreventive Agent

    • Bin Bao, Amir Ahmad, Azfar S Azmi, Zhiwei Wang, Sanjeev Banerjee, Fazlul H. Sarkar

    Pages 255-282

14. Diet-Induced Epigenetic Changes and Cancer Prevention: A Mantra for Healthy Living

    • Ajay Goel, Gaurav Chaturvedi

    Pages 283-326

15. Western Diet-Induced Pancreatic Cancer

    • M. Mura Assifi, Guido Eibl

    Pages 327-338

16. Intracellular Signaling Network as a Prime Chemotherapy Target of Green Tea Catechin, (–)-Epigallocatechin-3-gallate

    • Brahma N. Singh, Sharmila Shankar, Rakesh K. Srivastava

    Pages 339-376

17. Role of Dietary Antioxidants in Cancer

    • C. M. Ajila, S. K. Brar

    Pages 377-412

18. Curcumin: Structure, Biology and Clinical Applications

    • Sharmila Shankar, Rakesh K. Srivastava

    Pages 413-457

19. Obesity, Cancer and Psychopathology: Can Vegetarian Diet Be of Help?

    • Vikas Kumar, Ajit Kumar Thakur, Shyam Sunder Chatterjee

    Pages 459-491

20. Dietary Phytochemicals as Epigenetic Modulators in Cancer

    • Vijay S. Thakur, Sanjay Gupta

    Pages 493-519

Chemoprevention of cancer has been the focus of intensive research for more than two decades. Epidemiological evidence has shown a small, but significant association between fruit and vegetable intake and a reduction in cancer risk. Diet may account for about thirty five percent of cancer. Large claims have been made for the effectiveness of particular diets in determining one's risk of developing cancer, ranging from protection against cancer initiation, progression and metastasis. A wide array of dietary components has been demonstrated to be as effective in fighting off cancer. Towards an increased understanding of the nutrition, excercise and diet in preventing cancer or inhibiting its progression has led to the discovery and development of novel and effective drugs that regulate intracellular signaling network in the body. This information will be very useful to explore novel and highly effective chemopreventive strategies for reducing the health burden of cancer. Hippocrates, who proclaimed 25 centuries ago, 'Let food be thy medicine and medicine be thy food'. They estimated that one third of all cancer cases could be prevented by a healthier diet; statements which are widely accepted in the scientific literature. This book covers the current state-of-the art knowledge on the impact of nutrition and diet with nutrigenetics, nutritional epigenomics, nutritional transcriptomics, proteomics, and metabolomics approach in cancer prevention and therapy.

• Cancer
• Diet
• Excersice
• Nutrition
• Proteomice

• , Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, USA

  Sharmila Shankar

• , Pharmacology and Toxicology, University of Kansas Medical Center, Kansas City, USA

  Rakesh K. Srivastava

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