Springer eBooks may be purchased by end-customers only and are sold without copy protection (DRM free). Instead, all eBooks include personalized watermarks. This means you can read the Springer eBooks across numerous devices such as Laptops, eReaders, and tablets.
You can pay for Springer eBooks with Visa, Mastercard, American Express or Paypal.
After the purchase you can directly download the eBook file or read it online in our Springer eBook Reader. Furthermore your eBook will be stored in your MySpringer account. So you can always re-download your eBooks.
Mechanisms by which stem cell regulate regulate cellular function and normal organ development
Mechanisms by which cancer stem cells regulate cancer initiation and progression
Role of cancer stem cells in drug resistance
Signaling pathways regulating self-renewal capacity of normal stem cells and cancer stem cells
Development of novel drugs to target cancer stem cells
Role of microRNA and genes in stem cells and cancer stem cells
Genetic and proteomic profiling in stem cells
There have been major advances in understanding the behavior of stem cells and their roles in tissue regeneration, homeostasis and therapy. Cancer stem cell hypothesis opened a new opportunity for treating and preventing cancers by targeting cancer stem cells or cancer initiating cells. An increased understanding of stem cell behavior and biology along with rapid advancement of high throughput screening has led to the discovery and development of novel drugs that control stem cell self-renewal and differentiation. In near future, these molecules will be very useful for treating and preventing several human diseases.
While progress on the clinical front has been slower than desired, the use of stem cells for tissue regeneration and disease management has great potential in human health.
The first decade of the 21st century has brought with it significant progress in our understanding of stem cell or progenitor cells and their role in tissue regeneration and management of human diseases including cancer, neurodegenerative disorders, and heart diseases. This book covers the current state-of-the-art knowledge on the role of stem cells in tissue regeneration, homeostasis and disease management.
Coverage of the biology of stem cell and their role in tissue regeneration and organogenesis.
Mechanism-based strategies for stem cell self-renewal and differentiation.
Role of cancer stem cells or tumor initiating cells in cancer initiation, progression, relapse and drug resistance.
Use of stem cells in treating several human diseases, such as Alzheimer’s disease, Parkinson’s disease, cancer and diabetes.
Content Level »Research
Keywords »Cancer Stem Cells - Drug Resistance - Physiology and Metabolisms - Stem Cells - microRNA