Overview
- Editors:
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Marie-France Carlier
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, Laboratory of Structural Enzymology and, CNRS, Gif-sur-Yvette Cedex, France
- Covers insights coming from the various disciplines (cell biology, biochemistry, biophysics and theoretical modelling) that have contributed, in the past ten years, in understanding actin-based motility
- The application of the latest scientific techniques in the unraveling of cell motility
- A comprehensive understanding of actin-based cell motility
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Table of contents (17 chapters)
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Cellular Aspects
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- J. Victor Small, Klemens Rottner
Pages 3-33
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- Shiro Suetsugu, Tadaomi Takenawa
Pages 35-57
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- Andrea Disanza, Emanuela Frittoli, Chiara Giuliani, Francesca Milanesi, Andrea Palamidessi, Flavia Troglio et al.
Pages 59-84
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- Viveka Mayya, Michael L. Dustin
Pages 103-124
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- Matthew Oser, Robert Eddy, John Condeelis
Pages 125-164
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- Minna Roh-Johnson, Jessica Sullivan-Brown, Bob Goldstein
Pages 187-209
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Molecular Aspects
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Front Matter
Pages 211-211
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- Pekka Lappalainen, Maarit Makkonen, Hongxia Zhao
Pages 213-235
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- Marie-France Carlier, Dominique Pantaloni
Pages 237-254
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- David R. Kovar, Andrew J. Bestul, Yujie Li, Bonnie J. Scott
Pages 279-316
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Physical Aspects
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Front Matter
Pages 357-357
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- Ovijit Chaudhuri, Daniel A. Fletcher
Pages 359-379
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- Anders E. Carlsson, Alex Mogilner
Pages 381-412
About this book
Since the discovery of actin by Straub in the 1950’s and the pioneering work of Oosawa on actin self-assembly in helical laments in the 1960’s, many books and conference proceedings have been published. As one of the most essential p- teins in life, essential for movement in organisms rangingfrom bacteria to higher eukaryotes, it is no surprise that actin has fascinated generations of scientists from many different elds. Actin can be considered as a “living treasure” of biology; the kinetics and thermodynamics of self-assembly, the dissipative nature of actin po- merization, the molecular interactions of monomeric and polymerized actin with regulators, the mechanical properties of actin gels, and more recently the force p- ducing motile and morphogenetic processes organized by the actin nanomachine in response to signaling, are all milestones in actin research. Discoveries that directly derive from and provide deeper insight into the fundamental properties of actin are constantly being made, making actin an ever appealing research molecule. At the same time, the explosion in new technologies and techniques in biological sciences has served to attract researchers from an expanding number of disciplines, to study actin. This book presents the latest developments of these new multiscale approaches of force and movement powered by self-assembly processes, with the hope to opening our perspectives on the many areas of actin-based motility research.
Editors and Affiliations
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, Laboratory of Structural Enzymology and, CNRS, Gif-sur-Yvette Cedex, France
Marie-France Carlier
