Skip to main content
SpringerLink
Log in

The Networking of Chaperones by Co-chaperones

Control of Cellular Protein Homeostasis

  • Book
  • © 2015

Overview

Editors:
  1. Gregory Lloyd Blatch

    1. Victoria University, College of Health and Biomedicine, Melbourne, Australia

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Adrienne Lesley Edkins

    1. Department of Biochemistry and Microbiology, Rhodes University, Biomedical Biotechnology Research Unit, Grahamstown, South Africa

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • This is the only book that specifically reviews the knowledge on co-chaperones as opposed to chaperones
  • Excellent information resource for researchers entering the specialized field of cell stress and chaperones
  • Excellent information resource for researchers in the broader field of diseases related to protein folding (e.g. Alzheimers)
  • Includes supplementary material: sn.pub/extras

Part of the book series: Subcellular Biochemistry (SCBI, volume 78)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (12 chapters)

  1. Front Matter

    Pages i-xv
    Download chapter PDF

  2. GrpE, Hsp110/Grp170, HspBP1/Sil1 and BAG Domain Proteins: Nucleotide Exchange Factors for Hsp70 Molecular Chaperones

    • Andreas Bracher, Jacob Verghese
    Pages 1-33

  3. Functions of the Hsp90-Binding FKBP Immunophilins

    • Naihsuan C. Guy, Yenni A. Garcia, Jeffrey C. Sivils, Mario D. Galigniana, Marc B. Cox
    Pages 35-68

  4. Hsp70/Hsp90 Organising Protein (Hop): Beyond Interactions with Chaperones and Prion Proteins

    • Swati Baindur-Hudson, Adrienne L. Edkins, Gregory L. Blatch
    Pages 69-90

  5. Specification of Hsp70 Function by Type I and Type II Hsp40

    • Douglas M. Cyr, Carlos H. Ramos
    Pages 91-102

  6. Cdc37 as a Co-chaperone to Hsp90

    • Stuart K. Calderwood
    Pages 103-112

  7. p23 and Aha1

    • Alexandra Beatrice Rehn, Johannes Buchner
    Pages 113-131

  8. UCS Proteins: Chaperones for Myosin and Co-Chaperones for Hsp90

    • Weiming Ni, Odutayo O. Odunuga
    Pages 133-152

  9. Chaperonin—Co-chaperonin Interactions

    • Aileen Boshoff
    Pages 153-178

  10. Co-chaperones of the Mammalian Endoplasmic Reticulum

    • Armin Melnyk, Heiko Rieger, Richard Zimmermann
    Pages 179-200

  11. The Evolution and Function of Co-Chaperones in Mitochondria

    • Neta Regev-Rudzki, Kip Gabriel, Dejan Bursać
    Pages 201-217

  12. CHIP: A Co-chaperone for Degradation by the Proteasome

    • Adrienne L. Edkins
    Pages 219-242

  13. The Role of HSP70 and Its Co-chaperones in Protein Misfolding, Aggregation and Disease

    • Emma J. Duncan, Michael E. Cheetham, J. Paul Chapple, Jacqueline van der Spuy
    Pages 243-273

  14. Back Matter

    Pages 275-276
    Download chapter PDF
Back to top

Keywords

About this book

Co-chaperones are important mediators of the outcome of chaperone assisted protein homeostasis, which is a dynamic balance between the integrated processes of protein folding, degradation and translocation. The Networking of Chaperones by Co-chaperones describes how the function of the major molecular chaperones is regulated by a cohort of diverse non-client proteins, known as co-chaperones. The second edition includes the current status of the field and descriptions of a number of novel co-chaperones that have been recently identified. This new edition has a strong focus on the role of co-chaperones in human disease and as putative drug targets. The book will be a resource for both newcomers and established researchers in the field of cell stress and chaperones, as well as those interested in cross-cutting disciplines such as cellular networks and systems biology.

Editors and Affiliations

  • Victoria University, College of Health and Biomedicine, Melbourne, Australia

    Gregory Lloyd Blatch

  • Department of Biochemistry and Microbiology, Rhodes University, Biomedical Biotechnology Research Unit, Grahamstown, South Africa

    Adrienne Lesley Edkins

Bibliographic Information

  • Book Title: The Networking of Chaperones by Co-chaperones

  • Book Subtitle: Control of Cellular Protein Homeostasis

  • Editors: Gregory Lloyd Blatch, Adrienne Lesley Edkins

  • Series Title: Subcellular Biochemistry

  • DOI: https://doi.org/10.1007/978-3-319-11731-7

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing Switzerland 2015

  • Hardcover ISBN: 978-3-319-11730-0Published: 12 January 2015

  • Softcover ISBN: 978-3-319-38149-7Published: 24 September 2016

  • eBook ISBN: 978-3-319-11731-7Published: 08 December 2014

  • Series ISSN: 0306-0225

  • Series E-ISSN: 2542-8810

  • Edition Number: 1

  • Number of Pages: XV, 276

  • Number of Illustrations: 4 b/w illustrations, 31 illustrations in colour

  • Topics: Biomedicine general, Life Sciences, general, Biochemistry, general

Publish with us

Policies and ethics

Back to top

Search

Navigation