Overview
- Editors:
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Franz J. Hock
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CorDynamics, Dieburg, Germany
Covers classical and cutting-edge technologies, including methods & assessment of relevance
Updates readers with some 1,000 assays in an easy-to-use and uniform Format
Guides readers on testing and evaluating pharmacological effects of potential new drugs
Includes supplementary material: sn.pub/extras
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Table of contents (147 entries)
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Front Matter
Pages i-xxiii
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Cardiovascular Activity
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- Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
Pages 3-39
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- Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
Pages 41-133
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- Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
Pages 135-164
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- Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
Pages 165-216
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- Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
Pages 217-236
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- Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
Pages 237-286
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- Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
Pages 287-333
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- Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
Pages 335-347
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- Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
Pages 349-428
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- Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
Pages 429-472
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- Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
Pages 473-496
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- Liomar A. A. Neves, Olga Tiniakova
Pages 497-511
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- Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
Pages 513-553
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- Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
Pages 555-566
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- Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
Pages 567-586
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- Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
Pages 587-610
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- Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
Pages 611-644
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- Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
Pages 645-663
About this book
The 4th edition of this successful reference book contains an updated selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Effects covered include cardiovascular, analgesic, endocrine, psychotropic, respiratory, renal and immunomodulatory activities. Each of the more than 1,000 assays comprises a detailed protocol outlining the purpose and rationale of the method, a critical assessment of the results and their pharmacological and clinical relevance. In addition, animal models of rare diseases are described. For this 4th edition, all existing chapters have been revised and completely updated. A large number of assays were added. Sections that have been specifically enlarged include - Pharmacological assays in thrombosis and haemostasis, - Antidiabetic activity (includes completely new chapters such as Biochemical Methods in Diabetology), - Anti-atherosclerotic activity. New chapters are added such as Auditory Pharmacology, Oncology Activity, Stem Cells, Omics, Personalized Medicine, etc.
Editors and Affiliations
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CorDynamics, Dieburg, Germany
Franz J. Hock
About the editor
Since retiring from Aventis in 2002, Dr. Franz Jakob Hock has leveraged his experience as a freelance consultant specializing in Safety Pharmacology. Dr. Hock was a research scientist at Hoechst, Hoechst Marion Roussel and Aventis from 1976 – 2002. He lectured for several years at the University of Kassel und the Technical University of Darmstadt. Currently he is a member of the Task Force General/Safety Pharmacology German/Swiss Pharmaceutical Companies and a member of the Program Committee of the Safety Pharmacology Society.