Overview
- Presents the practice and problems associated with the use of pharmaceuticals in the extreme environment of spaceflight
Part of the book series: SpringerBriefs in Space Development (BRIEFSSPACE)
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Table of contents (10 chapters)
Keywords
About this book
Authors and Affiliations
About the author
Dr. Virginia Wotring is a Senior Scientist in the Division of Space Life Sciences at Universities Space Research Association, and Pharmacology Discipline Lead at NASA's Johnson Space Center, Human Health and Countermeasures. She received her doctorate in Pharmacological and Physiological Sciences at Saint Louis University after earning a BS in Chemistry at Florida State University. She has extensive experience studying drug mechanisms of action, drug receptor structure/function relationships, and gene and protein expression.
In 2009, she began directing the NASA JSC Pharmacology Lab, whose mission is to ensure that medications used during spaceflight will act in a predictable, effective and safe manner. The spaceflight environment includes several unusual stressors for the body: microgravity, fluid shifting, increased radiation exposure, lack of circadian cues and others. Each of these can alter normal physiology, and thus, change the way in which drugs are absorbed, distributed, metabolized, excreted or how they interact with physiological targets. Current projects include: determining cardiac safety of new and experimental anti-motion sickness combination therapies, and measurement of gene and protein expression after exposure to spaceflight or a gamma radiation analog of spaceflight.
Dr. Wotring is also actively involved in mentoring students and interns, and participates in teaching at area universities. She holds adjunct appointments in the UTMB Galveston Department of Pharmacology and Toxicology and at the University of Houston's Department of Health and Human Performance.
Bibliographic Information
Book Title: Space Pharmacology
Authors: Virginia E. Wotring
Series Title: SpringerBriefs in Space Development
DOI: https://doi.org/10.1007/978-1-4614-3396-5
Publisher: Springer New York, NY
eBook Packages: Physics and Astronomy, Physics and Astronomy (R0)
Copyright Information: Virginia E. Wotring 2012
Softcover ISBN: 978-1-4614-3395-8Published: 18 March 2012
eBook ISBN: 978-1-4614-3396-5Published: 15 March 2012
Series ISSN: 2191-8171
Series E-ISSN: 2191-818X
Edition Number: 1
Number of Pages: XI, 109
Number of Illustrations: 14 b/w illustrations, 9 illustrations in colour
Topics: Space Sciences (including Extraterrestrial Physics, Space Exploration and Astronautics), Pharmaceutical Sciences/Technology, Inorganic Chemistry