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Anticoagulants, Antiplatelets, and Thrombolytics

  • Book
  • © 2004

Overview

Editors:
  1. Shaker A. Mousa

    1. Albany College of Pharmacy, Albany

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Methods in Molecular Medicine (MIMM, volume 93)

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Table of contents (17 protocols)

  1. Front Matter

    Pages i-x
    Download chapter PDF

  2. Highlights of Latest Advances in Antithrombotics

    • Shaker A. Mousa
    Pages 1-7

  3. Antiplatelet, Anticoagulant, and Thrombolytic Drug Interactions

    • Omer Iqbal, Shaker A. Mousa
    Pages 9-20

  4. Evaluation of Platelet Antagonists in In Vitro Flow Models of Thrombosis

    • Owen J. T. McCarty, James P. Abulencia, Shaker A. Mousa, Konstantinos Konstantopoulos
    Pages 21-34

  5. Heparin and Low Molecular Weight Heparin in Thrombosis, Cancer, and Inflammatory Diseases

    • Shaker A. Mousa
    Pages 35-48

  6. Are Low Molecular Weight Heparins the Same?

    • Shaker A. Mousa
    Pages 49-59

  7. Antithrombotic Drugs for the Treatment of Heparin-Induced Thrombocytopenia

    • Walter P. Jeske, Jeanine M. Walenga
    Pages 61-82

  8. Laboratory Methods for Heparin-Induced Thrombocytopenia

    • Margaret Prechel, Walter P. Jeske, Jeanine M. Walenga
    Pages 83-93

  9. Factor Xa Inhibitors

    • Jeanine M. Walenga, Walter P. Jeske, Debra Hoppensteadt, Jawed Fareed
    Pages 95-117

  10. Tissue Factor/VIIa in Thrombosis and Cancer

    • Shaker A. Mousa
    Pages 119-132

  11. Tissue Factor Pathway Inhibitor in Thrombosis and Beyond

    • Shaker A. Mousa, Jawed Fareed, Omer Iqbal, Brigitte Kaiser
    Pages 133-155

  12. Cell Adhesion Molecules

    • Shaker A. Mousa
    Pages 157-174

  13. Development and Applications of Animal Models of Thrombosis

    • Ronald J. Shebuski, Larry R. Bush, Alison Gagnon, Liguo Chi, Robert J. Leadley Jr.
    Pages 175-219

  14. A Survey of Venous Thrombosis Models

    • Walter P. Jeske, Omer Iqbal, Jawed Fareed, Brigitte Kaiser
    Pages 221-237

  15. Arixtra® (Fondaparinux Sodium)

    • Shaker A. Mousa
    Pages 239-246

  16. Oral Thrombin Inhibitor Ximelagatran

    • Shaker A. Mousa
    Pages 247-251

  17. Pharmacogenomics and Coagulation Disorders

    • Omer Iqbal
    Pages 253-266

  18. Guidelines for Diagnosis and Treatment of Deep Venous Thrombosis and Pulmonary Embolism

    • Hikmat Abdel-Razeq, Mohamad Qari, Jorgen Kristensen, Hussein Alizeidah, Faisal Al-Sayegh, Mahmoud Marashi et al.
    Pages 267-292

  19. Back Matter

    Pages 293-307
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About this book

During the past decade, remarkable progress has been made in the development of new drugs to treat thrombotic and cardiovascular diseases, the number one cause of mortality worldwide. In Anticoagulants, Antiplatelets, and Thrombolytics, leading experts with established records of discovery and invention highlight the latest developments in antithrombotics and provide experimental methods for the discovery of new and improved anticoagulants. Among the cutting-edge developments reviewed are the novel usage of low molecular weight heparins, such antithrombin agents as hirudin, and such antiplatelet drugs as the GPIIb/IIIa inhibitors and ADP-receptor antagonists. Additional innovations discussed include aspirin and clopidogrel, the expanded use of polytherapeutic approaches, antiproteases (factors IIa, Xa, and VIIa), tissue-factor targeting, platelet-receptor targeting, and antithrombin III modulation. The authors also define the clinically relevant in vitro and in vivo models of thrombosis and hemostasis that led to these advances and that will surely aid in the discovery of the next generation of antithrombotics.
Up-to-date and forward-looking, Anticoagulants, Antiplatelets, and Thrombolytics illuminates the latest developments in the field of thrombosis and provides both basic and clinical investigators a broad array of successful experimental methods for the discovery and development of novel drugs to treat thrombotic and cardiovascular diseases.

Reviews

From the reviews:

"This book contains a number of informative topics on the latest advances in the field. … Basic science is completed with clinical results. Very complete guidelines for treatment of deep thrombosis and pulmonary embolism ends the book. This recommendable book … provides a clinical audience with a complete update on a major field in medicine." (Michel Telerman, Acta Cardiologica, April, 2005)

Editors and Affiliations

  • Albany College of Pharmacy, Albany

    Shaker A. Mousa

Bibliographic Information

  • Book Title: Anticoagulants, Antiplatelets, and Thrombolytics

  • Editors: Shaker A. Mousa

  • Series Title: Methods in Molecular Medicine

  • DOI: https://doi.org/10.1385/1592596584

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Humana Press 2004

  • eBook ISBN: 978-1-59259-658-4Published: 01 February 2008

  • Series ISSN: 1543-1894

  • Series E-ISSN: 1940-6037

  • Edition Number: 1

  • Number of Pages: X, 310

  • Topics: Hematology

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