Controversies in the Management of Gynecological Cancers

1. Front Matter

   Pages i-xv

   PDF

2. Controversies in the Treatment of Women with Early-Stage Epithelial Ovarian Cancer

   • Christina Fotopoulou, Ann Marie Swart, Robert L. Coleman

   Pages 1-15

3. Recurrent Ovarian Cancer: When to Treat and How to Assess

   • Rene Roux, Ignacio Romero, Martin Zweifel, Gordon Rustin, Robert C. Bast Jr.

   Pages 17-27

4. New Views of Ovarian Carcinoma Types: How Will This Change Practice?

   • Martin Köbel, Robert J. Kurman, Jeffrey D. Seidman

   Pages 29-38

5. Lymphadenectomy in Endometrial Cancer: The Controversy Rages Unabated

   • Henry C. Kitchener, Kristina A. Butler, Emma J. Crosbie, Andrea Mariani

   Pages 39-46

6. What Is the Role of Adjuvant Radiotherapy and Chemotherapy in Endometrial Cancer?

   • Thomas Hogberg, Carien L. Creutzberg

   Pages 47-57

7. Chemotherapy and/or Targeted Therapies for Advanced Endometrial Cancer: Time to Rethink?

   • Erica Stringer-Reasor, Gini Fleming, Daliah Tsoref, Amit Oza

   Pages 59-68

8. Is Cervix Cancer a Disappearing Disease? Impact of HPV Vaccination in Developed Countries

   • Karen Canfell, Julietta Patnick

   Pages 69-77

9. What Is the Role of Cytotoxic Chemotherapy in Advanced Cervical Cancer?

   • Alok Pant, Nobuyuki Susumu, Takafumi Toita, Satoru Sagae, William Small Jr.

   Pages 79-90

10. Response as a Measure of Treatment Efficacy in Clinical Trials: Should RECIST Be Abandoned?

    • Michael Friedlander, James Tate Thigpen

    Pages 91-100

11. What Are the Treatment Options for Recurrent Ovarian Cancer?

    • Jonathan A. Ledermann, Fharat A. Raja, Philipp Harter, Florian Heitz

    Pages 101-110

12. How to Study Rare Gynecological Tumors: Trials or Registries?

    • Isabelle Ray-Coquard, David M. Gershenson

    Pages 111-119

13. What Is the Best Treatment Model for Gynecologic Cancers? Does Centralization Help?

    • Claes Göran Tropé, Torbjørn Paulsen, Ayesha Saqib, Craig Underhill

    Pages 121-133

14. When Should Surgery Be Performed for the First-Line Treatment of Advanced Ovarian Cancer?

    • Ganendra Raj K. A. Mohan, Jane Hook, Jonathan A. Ledermann, Michael A. Quinn

    Pages 135-143

15. Does Intraperitoneal Therapy for Ovarian Cancer Have a Future?

    • Deborah K. Armstrong, Michael A. Bookman

    Pages 145-153

16. Maintenance Therapy for First-Line Treatment of Ovarian Cancer: Is This the Strategy for the Future?

    • Nicoletta Colombo, Lucas Minig, Robert Burger

    Pages 155-163

17. What Is the Value of Lymphadenectomy in Early Ovarian Cancer?

    • Sven Mahner, Jacobus Pfisterer, Ganendra Raj K. Ali Mohan, Michael A. Quinn

    Pages 165-173

18. Sentinel Node Biopsy—Does It Help in the Management of Vulvar Cancer?

    • Maaike H. M. Oonk, Ate G. J. van der Zee, Paul Speiser

    Pages 175-183

19. Controversies in the Management of Advanced Vulvar Cancer

    • Ericka Wiebe, Jacobus van der Velden, Gillian Thomas

    Pages 185-196

20. Bowel Obstruction in Ovarian Cancer: To Operate or Not?

    • Ram Eitan, Alexander de Graeff, Dennis S. Chi

    Pages 197-202

This is a novel text that highlights the controversial areas in the management of gynecological cancers. None of the topics in this book have definitive answers; they represent the everyday decision-making facing gynecologists, oncologists, radiologists, pathologists and other health professionals treating women with these conditions. This book is not to be used as a traditional textbook; it is a text that specialists and trainees will use to help them weigh up the arguments that exist in a variety of areas in the treatment of gynecological cancers. Each chapter will have two or more authors, selected either for their opposing views or for their ability to provide an opposite view or opinion to the other. The content will be evidence-based, illustrating contrasting evidence and scientific opinion in the literature. Each chapter will close on a summary indicating the direction of research needed to address the issues being discussed.

• Cervical
• Endometrial
• Gynecological
• Ovarian
• Vulval
• surgical oncology

From the book reviews:

“This book tackles current issues in the field of gynecological cancer. … The book is geared towards specialists in the field, although residents may find it useful. … The material is current and the data well done. This would be a good book for motivated trainees to bring to the table for discussions with attendings. Overall, the authors do a good job.” (Anthony Shanks, Doody’s Book Reviews, November, 2014)

• UCL Cancer Institute, University College London, London, United Kingdom

  Jonathan A. Ledermann

• Radiation Oncology, Leiden University Medical Center, Leiden, The Netherlands

  Carien L. Creutzberg

• Royal Women’s Hospital, The University of Melbourne, Melbourne, Australia

  Michael A. Quinn

Policies and ethics