Editors:
- Presents findings from the 2005 meeting Targeted Therapies in Cancer: Myth or Reality
- Reviews the move from empiricism to molecular targeted therapies and its effect on the development of new cancer therapies
- Offers readers an overview of diverse approaches, ranging from drug discovery to cellular therapy
- Includes supplementary material: sn.pub/extras
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 610)
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Table of contents (13 chapters)
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Front Matter
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Back Matter
About this book
In September 2005 an International Meeting on “Targeted Therapies in Cancer: Myth or Reality” was held in Milan. This successful Meeting was intended to represent a forum for scientists and clinicians working in cancer drug discovery and therapy to share their reflections and experiences on how the paradigm shift from empiricism to molecular targeted therapies is contributing to the translation of basic knowledge into new therapies for cancer patients. This book collects the contributions given by scientists and clinicians, from Academia and Industry, who participated to this Meeting.
We hope that this book contributes to improve our approach to cancer drug discovery and, ultimately, to find new, more efficacious and better tolerated drugs for cancer patients. It provides an overview of diverse approaches ranging from drug discovery to cellular therapy. Although this change in paradigm has been useful, its entry into the clinical arena was associates with unforeseen problems including the emergence of resistance, unexpected side effects and failures. Time is therefore ripe for a critical cultural reflection on the state of the art, prospects and limitations. Ultimately, is targeted therapy in cancer a myth or a reality?
Editors and Affiliations
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Nerviano Medical Sciences, Nerviano (Milano), Italy
Francesco Colotta
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Istituto Clinico Humanitas and Institute of Pathology, University of Milan, Rozzano, Milano, Italy
Alberto Mantovani
Bibliographic Information
Book Title: Targeted Therapies in Cancer:
Book Subtitle: Myth or Reality?
Editors: Francesco Colotta, Alberto Mantovani
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-0-387-73898-7
Publisher: Springer New York, NY
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2008
Hardcover ISBN: 978-0-387-73897-0Published: 10 December 2007
Softcover ISBN: 978-1-4419-2537-4Published: 29 November 2010
eBook ISBN: 978-0-387-73898-7Published: 05 December 2007
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: VIII, 191
Topics: Cancer Research, Human Genetics, Medicine/Public Health, general, Human Physiology, Developmental Biology