Overview
- Examines mechanisms underlying human somatic cell reprogramming to generate induced pluripotent stem cells
- Explains the use of endothelial progenitor cells and mesenchymal stem cells in renal repair
- Discusses mathematical models related to cancer stem cells and their use in studying stem cell differentiation
- Includes supplementary material: sn.pub/extras
Part of the book series: Stem Cells and Cancer Stem Cells (STEM, volume 12)
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Table of contents (21 chapters)
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Front Matter
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Pluripotent Stem Cells
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Front Matter
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Dendritic Cells
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Front Matter
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Regenerative Medicine
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Front Matter
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Keywords
About this book
Volume 12 in this series explores the latest experimental and clinical uses of stem cells in the treatment of disease and of injuries and reviews methods for isolating multipotent endothelial-like cells from human adipose tissue and discusses clinical applications in cell therapy and regenerative medicine.
The book is organized in five parts: Cancer Stem Cells, Pluripotent Stem Cells, Dendritic Stem Cells, Regenerative Medicine and General Applications. The first section includes chapters on histamine in the neural and cancer stem cell niches and emerging concepts of stem cell organization in the normal lung and in lung cancer. The section on Pluripotent Stem Cells includes discussion of the differentiation of dendritic cells from human induced pluripotent stem cell and the molecular mechanisms involved in reprogramming human somatic cells to generate induced pluripotent stem cells. Additional chapters cover the differentiation of induced pluripotent stem cells into functional cardiomyocytes, characteristics of satellite cells and multipotent adult stem cells in the skeletal muscle. The section on Dendritic Stem Cells explores the critical role of notch signaling in the differentiation and function of dendrite. Other chapters cover hypertensive emergencies in children after stem cell transplantation and overcoming the radio resistance of lung cancer stem cells. The section on Regenerative Medicine reports on experiments on improved renal revascularization in pigs using stem cells and phenotypic correction of murine Hemophilia A using cell-based therapy. The concluding section, General Applications, discusses such topics as methods in mathematical modeling for stem cells, as well as molecular and functional characterization of human adipocytes.
Like its eleven predecessors in the series, this volume stands out for its comprehensive approach, its roster of some 51 expert contributors representing a dozen different countries and its up-to-date review of leading-edge technology and methods.
Editors and Affiliations
Bibliographic Information
Book Title: Stem Cells and Cancer Stem Cells, Volume 12
Book Subtitle: Therapeutic Applications in Disease and Injury
Editors: M.A. Hayat
Series Title: Stem Cells and Cancer Stem Cells
DOI: https://doi.org/10.1007/978-94-017-8032-2
Publisher: Springer Dordrecht
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Science+Business Media Dordrecht 2014
Hardcover ISBN: 978-94-017-8031-5Published: 10 March 2014
Softcover ISBN: 978-94-024-0776-1Published: 18 September 2016
eBook ISBN: 978-94-017-8032-2Published: 20 February 2014
Series ISSN: 2215-0994
Series E-ISSN: 2215-1001
Edition Number: 1
Number of Pages: XLII, 256
Number of Illustrations: 4 b/w illustrations, 28 illustrations in colour
Topics: Cancer Research, Life Sciences, general, Oncology, Medicine/Public Health, general