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  • © 2014

Stem Cells and Cancer Stem Cells, Volume 11

Therapeutic Applications in Disease and injury

Editors:

  1. M.A. Hayat

    1. Department of Biological Sciences, Kean university, Room 213, Library Building, Union, USA

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  • Covers all varieties of stem cells: pluripotent, multipotent and unipotent cells Includes nine chapters devoted to cancer stem cells
  • Offers comprehensive review of the therapeutic application of stem cells for regeneration of bones, as biomarkers and in the treatment of the injured spinal cord
  • Expert contributors include oncologists, neurosurgeons, physicians, research scientists and pathologists

Part of the book series: Stem Cells and Cancer Stem Cells (STEM, volume 11)

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Table of contents (22 chapters)

  1. Front Matter

    Pages i-xxxviii
    PDF

  3. Cancer Stem Cells

    1. Front Matter

      Pages 65-65
      PDF

    3. Glioma Propagating Cells Show Enhanced Chemoresistance and Radioresistance (an Update)

      • Lynnette Wei Hsien Koh, Tan Boon Toh, Carol Tang, Beng Ti Ang
      Pages 75-91

    4. Chemical Genomic Approaches to Eradicate Leukemia Stem Cells

      • Siddhartha Sen, Monica L. Guzman, Duane C. Hassane
      Pages 93-101

    6. Cancer Stem Cells in Pediatric Sarcomas

      • Sampoorna Satheesha, Beat W. Schäfer
      Pages 111-126

    7. Cancer Stem Cells Derived from Mouse Induced Pluripotent Stem Cells

      • Hiroshi Murakami, Akifumi Mizutani, Chen Ling, Tomonari Kasai, Takayuki Kudoh, Li Fu et al.
      Pages 127-133

    8. Stemness Regulation of Somatic Cancer Cells

      • Zhenhe Suo, Jian-Guo Wen, Jahn M. Nesland
      Pages 135-147

    9. Induced Differentiation of Brain Tumour Stem Cells

      • Verena Kuchler, Euan S. Polson, Anjana Patel, Heiko Wurdak
      Pages 149-158

    11. Identification of Ovarian Cancer Stem Cells: Molecular Pathways

      • Arokia Priyanka Vaz, Parthasarathy Seshacharyulu, Surinder K. Batra, Moorthy P. Ponnusamy
      Pages 171-185

  4. Hematopoietic Stem Cells

    1. Front Matter

      Pages 187-187
      PDF

    2. Hematopoietic Stem Cells and Bone Regeneration

      • Reeva Aggarwal, Vincent J. Pompili, Hiranmoy Das
      Pages 189-200
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About this book

Volume 11 in this series discusses therapeutic applications of stem cells in disease and tissue injury. Coverage includes pluripotent stem cells, which can give rise to the endodermal, ectodermal, and mesodermal lineages; multipotent stem cells, which can generate all cells in a particular lineage and unipotent stem cells, which can give rise to only one cell type. This volume also examines cancer stem cells, tumor-initiating cells which possesses the capacity of self-renewal and can give rise to the heterogeneous lineages of cancer cells that comprise the tumor. Coverage extends to molecular mechanisms underlying the derivation and expansion of human embryonic stem cells, the role of specific proteins in the maintenance and inhibition of extraembryonic differentiation of these cells and the role of signaling responsible for the self-renewal of mouse embryonic stem cells. Nine chapters discuss the clinical importance of cancer stem cells, encompassing glioma, leukemia, ovarian cancer, pediatric sarcomas and head and neck squamous cell carcinoma. The role of cancer stem cells is also elucidated in epithelial-to-mesenchymal transition in spreading head and neck squamous cell carcinoma. The book goes on to survey therapeutic application of stem cells of hematopoietic and non-hematopoietic origin for regeneration of bones, including in osteoporotic bone disease; to illuminate the application of hematopoietic stem cells in bone regeneration and to discuss their use as a biomarker to facilitate determination of a treatment. The contributors review cells as biomarkers for pediatric solid tumors, and weigh the advantages and limitations of hematopoietic stem cell transplantation. Also included are details of neural stem cell engraftment in the injured spinal cord; the regenerative potential of neural stem/progenitor cells of newborns and cancer gene therapy potential using neural stem cells. Like the preceding volumes in the series, this book is distinguished for itscomprehensive approach, its distinguished roster of 58 contributors representing 10 different countries and its thorough review of leading-edge technology and methods.
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Keywords

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Editors and Affiliations

  • Department of Biological Sciences, Kean university, Room 213, Library Building, Union, USA

    M.A. Hayat

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Bibliographic Information

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Buy it now

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

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