Developing Synthetic Transport Systems

1. Front Matter

   Pages i-vii

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2. Biological Cybernetics and the Optimization Problem of Transport of Substances in Cells

   • Alexey Melkikh, Maria Sutormina

   Pages 1-34

3. Models of Ion Transport in Mammalian Cells

   • Alexey Melkikh, Maria Sutormina

   Pages 35-83

4. Models of Ion Transport and Regulation in Plant Cells and Unicellular Organisms

   • Alexey Melkikh, Maria Sutormina

   Pages 85-130

5. Optimization of the Transport of Substances in Cells

   • Alexey Melkikh, Maria Sutormina

   Pages 131-197

6. Back Matter

   Pages 199-199

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​Understanding the general laws of an effective system for the transport of substances in cells is an important goal of systems and synthetic biology and will help us to answer why the transport subsystem of a cell is arranged as it is. In addition, the construction of models for optimizing transport systems is of considerable importance in the early stages in the development of a functioning protocell. The aim of this book is to describe the latest techniques for the calculation of the optimal parameters of the transport subsystem of a cell at its maximum efficiency. The book will describe linear and nonlinear programming, dynamic programming, game theory for models of ion transport in different types of cells (e.g. mammalian cells, bacteria, plants and fungi). ​

• Game theory
• Ion transport
• Linear programming
• Minimal Cell
• Systems Biology

• Institute of Physics and Technology, Ural Federai University, Yekaterinburg, Russia

  Alexey Melkikh

• Institute of Technology, Department of Physics, Ural Fedrai University, Yekaterinburg, Russia

  Maria Sutormina

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