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Computer Models in Biomechanics

From Nano to Macro

  • Conference proceedings
  • © 2013

Overview

Editors:
  1. Gerhard A. Holzapfel

    1. Institute of Biomechanics, Center of Biomedical Engineering, Graz University of Technology, Graz, Austria

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  2. Ellen Kuhl

    1. Dept. Mechanical Engineering, Dept. of Bioengineering (courtesy), Stanford University, Stanford, USA

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    You can also search for this editor in PubMed   Google Scholar

  • Topic is one of the most exciting and challenging problems of mechanics in the 21st century
  • Collects state-of-the-art work
  • Contributions of the best scientists worldwide working in this particular field
  • Includes supplementary material: sn.pub/extras

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Table of contents (28 papers)

  1. Front Matter

    Pages I-XI
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  2. Protein and Cell Mechanics

    1. Front Matter

      Pages 1-1
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    2. Towards a Coarse-Grained Model for Unfolded Proteins

      • Ali Ghavami, Erik Van der Giessen, Patrick R. Onck
      Pages 3-10

    3. Modeling Collagen-Proteoglycan Structural Interactions in the Human Cornea

      • Xi Cheng, Hamed Hatami-Marbini, Peter M. Pinsky
      Pages 11-24

    4. Simulations of Cell Behavior on Substrates of Variegated Stiffness and Architecture

      • Amit Pathak, Vikram S. Deshpande, Anthony G. Evans, Robert M. McMeeking
      Pages 25-41

  3. Muscle Mechanics

    1. Front Matter

      Pages 43-43
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    2. A Mathematical Approach for Studying Ca2+-Regulated Smooth Muscle Contraction

      • Saeil C. Murtada, Gerhard A. Holzapfel
      Pages 45-62

    3. A Coupled Chemomechanical Model for Smooth Muscle Contraction

      • Markus Böl, Andre Schmitz
      Pages 63-75

    4. Modeling of Smooth Muscle Activation

      • Jonas Stålhand, Anders Klarbring, Gerhard A. Holzapfel
      Pages 77-89

    5. A Cross-Bridge Model Describing the Mechanoenergetics of Actomyosin Interaction

      • Mari Kalda, Pearu Peterson, Jüri Engelbrecht, Marko Vendelin
      Pages 91-102

    6. Multiscale Skeletal Muscle Modeling: From Cellular Level to a Multi-segment Skeletal Muscle Model of the Upper Limb

      • Oliver Röhrle, Michael Sprenger, Ellankavi Ramasamy, Thomas Heidlauf
      Pages 103-116

  4. Cardiovascular Mechanics

    1. Front Matter

      Pages 117-117
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  5. CardiovascularMechanics

    1. Multiscale Modeling of Arterial Adaptations: Incorporating Molecular Mechanisms Within Continuum Biomechanical Models

      • Jay D. Humphrey
      Pages 119-127

    2. Cardiovascular Tissue Damage: An Experimental and Computational Framework

      • Nele Famaey, Ellen Kuhl, Gerhard A. Holzapfel, Jos Vander Sloten
      Pages 129-148

    3. Mechanical Properties of Ascending Thoracic Aortic Aneurysm (ATAA): Association with Valve Morphology

      • Salvatore Pasta, Julie A. Phillipi, Thomas G. Gleason, David A. Vorp
      Pages 149-160

    4. Intracranial Aneurysms: Modeling Inception and Enlargement

      • Paul N. Watton, Haoyu Chen, Alisa Selimovic, Harry Thompson, Yiannis Ventikos
      Pages 161-173

    5. Micro-structurally Based Kinematic Approaches to Electromechanics of the Heart

      • Serdar Göktepe, Andreas Menzel, Ellen Kuhl
      Pages 175-187

    6. Activation Models for the Numerical Simulation of Cardiac Electromechanical Interactions

      • Ricardo Ruiz-Baier, Davide Ambrosi, Simone Pezzuto, Simone Rossi, Alfio Quarteroni
      Pages 189-201

    7. Hemodynamic Alterations Associated with Coronary and Cerebral Arterial Remodeling Following a Surgically-Induced Aortic Coarctation

      • C. Alberto Figueroa, Jessica S. Coogan, Jay D. Humphrey
      Pages 203-216

    8. Patient-Specific Surgery Planning for the Fontan Procedure

      • Christopher M. Haggerty, Lucia Mirabella, Maria Restrepo, Diane A. de Zélicourt, Jarek Rossignac, Fotis Sotiropoulos et al.
      Pages 217-228
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Keywords

About this book

This book contains a collection of papers that were presented at the IUTAM Symposium

on “Computer Models in Biomechanics: From Nano to Macro” held at Stanford University, California, USA, from August 29 to September 2, 2011.

It contains state-of-the-art papers on:

- Protein and Cell Mechanics: coarse-grained model for unfolded proteins, collagen-proteoglycan structural interactions in the cornea, simulations of cell behavior on substrates

- Muscle Mechanics: modeling approaches for Ca2+–regulated smooth muscle contraction, smooth muscle modeling using continuum thermodynamical frameworks, cross-bridge model describing the mechanoenergetics of actomyosin interaction, multiscale skeletal muscle modeling

- Cardiovascular Mechanics: multiscale modeling of arterial adaptations by incorporating molecular mechanisms, cardiovascular tissue damage, dissection properties of aortic aneurysms, intracranial aneurysms, electromechanics of the heart, hemodynamic alterations associated with arterial remodeling following aortic coarctation, patient-specific surgery planning for the Fontan procedure

- Multiphasic Models: solutes in hydrated biological tissues, reformulation of mixture theory-based poroelasticity for interstitial tissue growth, tumor therapies of brain tissue, remodeling of microcirculation in liver lobes, reactions, mass transport and mechanics of tumor growth, water transport modeling in the brain, crack modeling of swelling porous media

- Morphogenesis, Biological Tissues and Organs: mechanisms of brain morphogenesis, micromechanical modeling of anterior cruciate ligaments, mechanical characterization of the human liver, in vivo validation of predictive models for bone remodeling and mechanobiology, bridging scales in respiratory mechanics

Editors and Affiliations

  • Institute of Biomechanics, Center of Biomedical Engineering, Graz University of Technology, Graz, Austria

    Gerhard A. Holzapfel

  • Dept. Mechanical Engineering, Dept. of Bioengineering (courtesy), Stanford University, Stanford, USA

    Ellen Kuhl

Bibliographic Information

  • Book Title: Computer Models in Biomechanics

  • Book Subtitle: From Nano to Macro

  • Editors: Gerhard A. Holzapfel, Ellen Kuhl

  • DOI: https://doi.org/10.1007/978-94-007-5464-5

  • Publisher: Springer Dordrecht

  • eBook Packages: Engineering, Engineering (R0)

  • Copyright Information: Springer Science+Business Media Dordrecht 2013

  • Hardcover ISBN: 978-94-007-5463-8Published: 17 October 2012

  • Softcover ISBN: 978-94-007-9450-4Published: 09 November 2014

  • eBook ISBN: 978-94-007-5464-5Published: 16 October 2012

  • Edition Number: 1

  • Number of Pages: XII, 416

  • Topics: Theoretical and Applied Mechanics, Biomedicine general, Mathematical Modeling and Industrial Mathematics

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