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Pediatric Cancer, Volume 2

Teratoid/Rhabdoid, Brain Tumors, and Glioma

  • Book
  • © 2012

Overview

Editors:
  1. M.A. Hayat

    1. , Kean University, Room 213, Library building, Union, USA

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  • Epilepsy treatment and prognosis
  • Symptoms of tumors in children
  • Diagnostic imaging technology
  • Differences between tumors in adults and children
  • Color illustrations

Part of the book series: Pediatric Cancer (PECA, volume 2)

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Table of contents (30 chapters)

  1. Front Matter

    Pages i-xxii
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  2. Teratoid/Rhabdoid

    1. Front Matter

      Pages 1-1
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  3. TERATOID/RHABDOID

    1. Pediatric Atypical Teratoid/Rhabdoid Tumors (An Overview)

      • Krishan Kumar Bansal, Deepak Goel
      Pages 3-11

    2. Pediatric Atypical Teratoid/Rhabdoid Tumor

      • Korgun Koral, Daniel C. Bowers
      Pages 13-21

    3. Pediatric Rhabdomyosarcoma: Role of Cell Cycle Regulators Alteration

      • Kenichi Kohashi, Yukiko Takahashi, Tomoaki Taguchi, Yoshinao Oda
      Pages 23-30

    4. Pediatric Atypical Teratoid/Rhabdoid Tumors: Imaging with CT and MRI

      • Monika Warmuth-Metz, Michael Frühwald
      Pages 31-37

    5. Pediatric Atypical Teratoid/Rhabdoid Tumor: Diagnosis Using Imaging Techniques and Histopathology

      • Fabrice Bing
      Pages 39-51

    6. Pediatric Atypical Teratoid/Rhabdoid Tumors: Differential Diagnosis

      • Justin A. Bishop, Syed Z. Ali
      Pages 53-58

  4. Brain Tumors (General)

    1. Front Matter

      Pages 59-59
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  5. BRAIN TUMORS (GENERAL)

    1. Pediatric Brain Tumors (An Overview)

      • Eugene I. Hwang, Roger J. Packer
      Pages 61-73

    2. Pediatric CNS Primitive Neuroectodermal Tumor: Role of the WNT Pathway

      • Hazel A. Rogers, Richard G. Grundy
      Pages 75-87

    3. Neuroblastic Tumors – Status and Role of HER Family Receptors

      • Ewa Izycka-Swieszewska, Agnieszka Wozniak
      Pages 89-98

    4. Children with Neurofi bromatosis Type 1: Positron Emission Tomography

      • Kevin London, Mahendra Moharir, Kathryn North, Robert Howman-Giles
      Pages 99-105

    5. Metabolite Profile Differences in Childhood Brain Tumors: 1H Magic Angle Spinning NMR Spectroscopy

      • Martin Wilson, Andrew Peet
      Pages 107-116

    6. Central Nervous System Imaging in Childhood Leukemia

      • Luciana Porto, Heinrich Lanfermann
      Pages 117-128

    7. Immunohistochemistry in the Differential Diagnosis of Adult and Pediatric Brain Tumors

      • Aditya Raghunathan
      Pages 129-141

    8. Children with Brain Tumors: Role of the Neurosurgeon

      • Peter F. Morgenstern, Mark M. Souweidane
      Pages 143-154

    9. Pediatric Intraventricular Brain Tumors: Endoscopic Neurosurgical Techniques

      • David I. Sandberg, Faiz Ahmad
      Pages 155-163

    10. Neurosurgical Management of Pediatric Brain Tumors

      • Mehdi Shahideh, George M. Ibrahim, James T. Rutka
      Pages 165-177

    11. Pediatric Brain Tumor Biopsy or Resection: Use of Postoperative Nonnarcotic Analgesic Medication

      • R. Shane Tubbs, Martin M. Mortazavi, Aaron A. Cohen-Gadol
      Pages 179-182
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Keywords

About this book

A general introduction to the principles of diagnosis and treatment of children with brain tumors is presented. Molecular characterization of solid tumors is also presented. Molecular pathways provide putative targets for new therapies. High resolution magic spinning NMR spectroscopy is explained, which is used to determine metabolic profiles for small pieces of intact tissue and whole cells in culture. The differences between adult and pediatric brain tumors are outlined. It is emphasized that pediatric low-grade gliomas need lower doses of antidrugs such as cisplatin/etoposide. It is explained that tumor suppressor genes and oncogenes play a crucial role in the development and progression of human malignancies, including those in children. Neurofibromatosis type-1 is a common genetic disorder with a high prevalence in CNS abnormalities including tumors in children; which is discussed in detail. Various neuroradiological imaging modalities in children with leukemia are detailed. Also are detailed results of clinical trials in pediatric brain tumors, such as medulloblastoma, ependymoma, craniopharyngioma, low-grade glioma, high-grade glioma, brainstem glioma, and germ cell tumors, using radiotherapy. Considering the clinical importance of epilepsy in the primary brain tumors in children, its symptoms, diagnosis, and treatments (surgery and antiepileptic drugs) are discussed.

Editors and Affiliations

  • , Kean University, Room 213, Library building, Union, USA

    M.A. Hayat

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