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The Busy Physician’s Guide To Genetics, Genomics and Personalized Medicine

  • Book
  • © 2011

Overview

Authors:
  1. Kevin M. Sweet

    1. The Ohio State University, Division of Human Genetics, Clinical Cancer Genetic and Medical Gene, Columbus, USA

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    You can also search for this author in PubMed   Google Scholar

  2. Ron C. Michaelis

    1. , Department of Biology--132 NS, Western Carolina University, Cullowhee, USA

    View author publications

    You can also search for this author in PubMed   Google Scholar

  • Comprehensive review of the genetic/genomic principles underlying personalized medicine
  • Wide-ranging review of current progress in personalized medicine for common, complex disease Concise, to-the-point coverage written in an easy-to-read writing style
  • Listing of valuable online resources to apply in patient risk assessment and personalized medicine

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Table of contents (7 chapters)

  1. Front Matter

    Pages i-xxiv
    Download chapter PDF

  2. Genetic Variability Provides the Biochemical Basis for Our Individuality, Including Differences in Our Susceptibility to Many Common Diseases

    • Kevin M. Sweet, Ron C. Michaelis
    Pages 1-34

  3. Making the Most of Family History Information, Single Gene Disorders and Mendelian Patterns of Inheritance, and When to Refer to a Genetic Specialist

    • Kevin M. Sweet, Ron C. Michaelis
    Pages 35-49

  4. Types of Genetic Tests and Issues Associated with the Interpretation of Their Results

    • Kevin M. Sweet, Ron C. Michaelis
    Pages 51-83

  5. Toward the Safer and More Effective Use of Prescription Drugs: Pharmacogenetics

    • Kevin M. Sweet, Ron C. Michaelis
    Pages 85-106

  6. Taking a Personalized Medicine Approach to Breast and Colon Cancer

    • Kevin M. Sweet, Ron C. Michaelis
    Pages 107-139

  7. Personalizing Risk Assessments and Treatments for Complex Cardiovascular Disease

    • Kevin M. Sweet, Ron C. Michaelis
    Pages 141-172

  8. Other Multifactorial Disorders for Which Genetic/Genomic Testing Is Providing Insights

    • Kevin M. Sweet, Ron C. Michaelis
    Pages 173-198

  9. Back Matter

    Pages 199-211
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Keywords

About this book

In the coming decade, the focus of medicine will shift from a disease-oriented approach, where the physician prescribes according to the disease the patient has, to a personalized approach, in which the physician first considers the patient’s individual biochemistry before prescribing a treatment. Personalized medicine has the potential to improve efficacy and safety in virtually all fields of medicine. Unfortunately, few physicians feel confident in their ability to apply the principles of genetics and genomics upon which personalized medicine is based to their practice. This book is intended to help the practicing physician understand and apply the principles of genetic and genomic medicine, regardless of his/her level of background in the field. It provides a thorough foundation/review of classical genetic principles, with an emphasis on how these principles apply to personalized medicine and common complex diseases. In addition, it provides a wide-ranging review of the inroads that personalized medicine has made into several fields, including cancer, psychiatric disorders, cardiovascular disease, substance abuse, Alzheimer disease, respiratory diseases, type 2 diabetes and macular degeneration. Most importantly, this book is intended to enable the practicing physician, physician assistants and their entire healthcare team to anticipate the developments that will emerge in the near future, and stay current with the field as it expands.

Reviews

“This is a timely book about personalized genomic medicine. … is essential for the physician farther out from training who may not be up to date with genetic advances made in the last decade and is also a helpful refresher for the more recent graduate. … this book would make a great addition to a personal physician’s library as a reference book. … a great addition to a medical school or residency program library.” (Laura Shaw, Family Medicine, Vol. 45 (10), November-December, 2013)

“The book offers the reader a bird’s eye view of the broad field of genetics and genomics and its application to personalized medicine. It will prove as an enjoyable reading for both practicing physicians as well as students interested to venture into the vast and interesting field of genetics and genomics.” (Ashwin Dalal, IndianJournal of Medical Research, Vol. 136, July, 2012)

Authors and Affiliations

  • The Ohio State University, Division of Human Genetics, Clinical Cancer Genetic and Medical Gene, Columbus, USA

    Kevin M. Sweet

  • , Department of Biology--132 NS, Western Carolina University, Cullowhee, USA

    Ron C. Michaelis

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