Editors:
- Soup-to-nuts overview not provided by any other book
- Objective, high-level, genome-based viewpoint, with subsidiary examples, rather than “paradigm by anecdote”
- Combines in-depth analysis of molecular biology literature with computational-based large-scale analyses
Part of the book series: Subcellular Biochemistry (SCBI, volume 52)
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Table of contents (13 chapters)
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Front Matter
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Back Matter
About this book
Transcription factors are the molecules that the cell uses to interpret the genome: they possess sequence-specific DNA-binding activity, and either directly or indirectly influence the transcription of genes. In aggregate, transcription factors control gene expression and genome organization, and play a pivotal role in many aspects of physiology and evolution.
This book provides a reference for major aspects of transcription factor function, encompassing a general catalogue of known transcription factor classes, origins and evolution of specific transcription factor types, methods for studying transcription factor binding sites in vitro, in vivo, and in silico, and mechanisms of interaction with chromatin and RNA polymerase.
Editors and Affiliations
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, Centre for Cellular and Biomolecular Res, University of Toronto, Toronto, Canada
Timothy R. Hughes
Bibliographic Information
Book Title: A Handbook of Transcription Factors
Editors: Timothy R. Hughes
Series Title: Subcellular Biochemistry
DOI: https://doi.org/10.1007/978-90-481-9069-0
Publisher: Springer Dordrecht
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Science+Business Media B.V. 2011
Hardcover ISBN: 978-90-481-9068-3Published: 12 May 2011
Softcover ISBN: 978-94-007-3604-7Published: 15 July 2013
eBook ISBN: 978-90-481-9069-0Published: 10 May 2011
Series ISSN: 0306-0225
Series E-ISSN: 2542-8810
Edition Number: 1
Number of Pages: XIV, 306
Topics: Biomedicine general, Biochemistry, general, Nucleic Acid Chemistry, Cell Biology