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  • © 2010

Cholesterol Binding and Cholesterol Transport Proteins:

Structure and Function in Health and Disease

Editors:

  • This book covers all currently significant aspects of cholesterol-binding and transport proteins
  • This book integrates diverse topics under the theme of the title
  • Chapters in this book are written by active scientists in their field of study
  • This book contains a thorough coverage of both fundamental science and clinical aspects of cholesterol-binding proteins
  • This book fills a unique gap in the cholesterol literature by placing emphasis upon the proteins associated with cholesterol

Part of the book series: Subcellular Biochemistry (SCBI, volume 51)

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Table of contents (22 chapters)

  1. Front Matter

    Pages i-xxi
  2. Cholesterol in Alzheimer’s Disease and other Amyloidogenic Disorders

    • J. Robin Harris, Nathaniel G.N. Milton
    Pages 47-75
  3. Sterol–Protein Interactions in Cholesterol and Bile Acid Synthesis

    • Emma De Fabiani, Nico Mitro, Federica Gilardi, Maurizio Crestani
    Pages 109-135
  4. Cholesterol Oxidase: Structure and Function

    • Alice Vrielink
    Pages 137-158
  5. Oxysterol-Binding Proteins

    • Neale D. Ridgway
    Pages 159-182
  6. Lipoprotein Modification and Macrophage Uptake: Role of Pathologic Cholesterol Transport in Atherogenesis

    • Yury I. Miller, Soo-Ho Choi, Longhou Fang, Sotirios Tsimikas
    Pages 229-251
  7. Cholesterol Interaction with Proteins That Partition into Membrane Domains: An Overview

    • Richard M. Epand, Annick Thomas, Robert Brasseur, Raquel F. Epand
    Pages 253-278
  8. Caveolin, Sterol Carrier Protein-2, Membrane Cholesterol-Rich Microdomains and Intracellular Cholesterol Trafficking

    • Friedhelm Schroeder, Huan Huang, Avery L. McIntosh, Barbara P. Atshaves, Gregory G. Martin, Ann B. Kier
    Pages 279-318
  9. Cholesterol in Niemann–Pick Type C disease

    • Xiaoning Bi, Guanghong Liao
    Pages 319-335
  10. Prominin-1: A Distinct Cholesterol-Binding Membrane Protein and the Organisation of the Apical Plasma Membrane of Epithelial Cells

    • Denis Corbeil, Anne-Marie Marzesco, Christine A. Fargeas, Wieland B. Huttner
    Pages 399-423
  11. Membrane Cholesterol in the Function and Organization of G-Protein Coupled Receptors

    • Yamuna Devi Paila, Amitabha Chattopadhyay
    Pages 439-466
  12. Cholesterol and Myelin Biogenesis

    • Gesine Saher, Mikael Simons
    Pages 489-508
  13. Cholesterol and Ion Channels

    • Irena Levitan, Yun Fang, Avia Rosenhouse-Dantsker, Victor Romanenko
    Pages 509-549

About this book

Knowledge of cholesterol and its interaction with protein molecules is of fundamental importance in both animal and human biology. This book contains 22 chapters, dealing in depth with structural and functional aspects of the currently known and extremely diverse unrelated families of cholesterol-binding and cholesterol transport proteins. By drawing together this range of topics the Editor has attempted to correlate this broad field of study for the first time. Technical aspects are given considerable emphasis, particularly in relation cholesterol reporter molecules and to the isolation and study of membrane cholesterol- and sphingomyelin-rich "raft" domains. Cell biological, biochemical and clinical topics are included in this book, which serve to emphasize the acknowledged and important benefits to be gained from the study of cholesterol and cholesterol-binding proteins within the biomedical sciences and the involvement of cholesterol in several clinical disorders.

It is hoped that by presenting this topic in this integrated manner that an appreciation of the fact that there is much more that needs to be taken into account, studied and understood than the widely discussed "bad and good cholesterol" associated, respectively, with the low- and high-density lipoproteins, LDL and HDL.

Editors and Affiliations

  • Hexham, Northumberland, United Kingdom

    J. Robin Harris

Bibliographic Information

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access