Overview
- Provides an authoritative review of this highly active area of research on programmed cell death
- Discusses issues of significance of apoptosome such as its structure, composition and regulation
- Reviews the preclinical and clinical applications of apoptosome regulation
- A useful resource for molecular and cell biologist, as well as for scientist and the academic/industry community
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Table of contents (16 chapters)
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Front Matter
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Back Matter
Keywords
About this book
"Apoptosome" is the first book that presents a concise synthesis of recent developments in the understanding of how the activation of the cell death cascade is handled by a cytosolic signalling platform known as the apoptosome.
The book also discusses how insights into the regulation of apoptosome may be exploited for designing new drugs aimed at interfere with a plethora of pathogenetic processes involved in human diseases.
The authors emphasize novel translational approaches that are rapidly moving from the laboratory bench top to the patient's bedside for the future treatment of diseases associated with apoptosis.
This book will be a valuable resource for researchers investigating the role of apoptosome-dependent cell death in cancer and other diseases, for researchers investigating the molecular mechanism of chemotherapeutic agents and drug-resistance and for physicians using chemotherapeutic agents. Additionally, this book will be an important educational source for PhD students and MD students specializing in molecular and cell biology, and to anybody interested in science, medicine, as well as in recent developments of the ideas and concepts of the molecular biology of programmed cell death.
Editors and Affiliations
Bibliographic Information
Book Title: Apoptosome
Book Subtitle: An up-and-coming therapeutical tool
Editors: Francesco Cecconi, Marcello D'Amelio
DOI: https://doi.org/10.1007/978-90-481-3415-1
Publisher: Springer Dordrecht
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Science+Business Media B.V. 2010
Hardcover ISBN: 978-90-481-3414-4Published: 18 December 2009
Softcover ISBN: 978-94-007-9090-2Published: 23 November 2014
eBook ISBN: 978-90-481-3415-1Published: 01 December 2009
Edition Number: 1
Number of Pages: X, 322
Topics: Cancer Research, Oncology, Cell Biology, Pharmacology/Toxicology, Apoptosis