Stem Cell Biology in Health and Disease

1. Front Matter

   Pages i-xii

   PDF

2. Bone marrow-derived stem cells

   1. Front Matter

      Pages 9-9

      PDF

   2. Introduction

      • Thomas Dittmar, Kurt S. Zänker

      Pages 1-7

   3. Hematopoietic Stem and Progenitor Cells in Clinical Use – Transplantation and Mobilization

      • Michael Punzel

      Pages 11-26

   4. Ex Vivo Expansion of HSPCs

      • Yaming Wei, Xin Ye

      Pages 27-56

   5. Modulation of Hematopoietic Stem/Progenitor Cell Migration

      • Thomas Dittmar, Susannah H. Kassmer, Benjamin Kasenda, Jeanette Seidel, Bernd Niggemann, Kurt S. Zänker

      Pages 57-77

   6. Properties of Mesenchymal Stem Cells to Consider for Cancer Cell Therapy

      • John Stagg, Sandra Pommey

      Pages 79-98

3. Embryonic Stem Cells

   1. Front Matter

      Pages 99-99

      PDF

   2. Alternative Embryonic Stem Cell Sources

      • Tomo Šarić, Narges Zare Mehrjardi, Jürgen Hescheler

      Pages 101-143

   3. Cell Therapy in Parkinson’s Disease

      • R. Laguna Goya, R.A. Barker

      Pages 145-154

   4. Transplantation of Stem Cells and Their Derivatives in the Treatment of Multiple Sclerosis

      • Eric C. Larsen, Ian D. Duncan

      Pages 155-181

4. Cancer Stem Cells

   1. Front Matter

      Pages 183-183

      PDF

   2. Cancer: A Stem Cell-based Disease?

      • James E. Trosko

      Pages 185-222

   3. Stem Cell Niche Versus Cancer Stem Cell Niche – Differences and Similarities

      • Bruce C. Baguley, Graeme J. Finlay

      Pages 223-233

   4. The Chronically Inflamed Microenvironment and Cancer Stem Cells

      • Hanchen Li, Calin Stoicov, Xueli Fan, Jan Cerny, Jean Marie Houghton

      Pages 235-250

   5. Does the Chronically Inflamed Periodontium Harbour Cancer Stem Cells?

      • Wolf-Dieter Grimm, Wolfgang H. Arnold, Sebastian Becher, Aous Dannan, Georg Gassmann, Stathis Philippou et al.

      Pages 251-279

   6. Leukemia Stem Cells

      • Markus Müschen

      Pages 281-294

   7. Cancer Stem Cells in Solid Tumors

      • Melia G. Nafus, Alexander Yu. Nikitin

      Pages 295-326

   8. “One for All” or “All for One”? – The Necessity of Cancer Stem Cell Diversity in Metastasis Formation and Cancer Relapse

      • Thomas Dittmar, Christa Nagler, Sarah Schwitalla, Kathrin Krause, Jeanette Seidel, Georg Reith et al.

      Pages 327-356

   9. Elimination of Cancer Stem Cells

      • A. Sagrera, J. Pérez-Losada, M. Pérez-Caro, R. Jiménez, I. Sánchez-García, C. Cobaleda

      Pages 357-384

Stem Cell Biology in Health and Disease presents an up-to-date overview about the dual role of stem cells in health and disease. The Editors have drawn together an international team of experts providing chapters which, in this fully-illustrated volume, discuss:

- the controversial debate on the great expectations concerning stem cell based regeneration therapies raised by the pluripotency of various stem cells.
- the advantages and concerns about embryonic stem cells (ES cells), induced pluripotent stem cells (iPS cells) and adult stem cells, such as bone marrow-derived stem cells (BMDCs).
- the type of stem cells, which has become of interest in the past decade, namely so-called cancer stem cells (CSCs). CSCs are now in the focus of cancer research since the eradication of tumour initiating cells would raise the changes of definitely cure cancer.

Professor Dittmar and Professor Zänker have edited a must-read book for researchers and professionals working in the field of regenerative medicine and/or cancer.

• Stem Cell
• Vivo
• cell biology
• migration
• transplantation

Aus den Rezensionen: “Ein Überblick zu Stammzellen in ihren verschiedenen Rollen bei Regeneration und Krebs? Ambitioniert. ... Das liegt einerseits am medium Buch. Ästhetisch ansprechend, nur dauert es eine Weile, bis es zusammengestellt und gedruckt ist. ... Viele wissenschaftliche Erkenntnisse sind beeindruckend, wenn sie zum ersten Mal geäußert werden ... Im einleitenden geschichtlichen Überblick stammen die aktuellsten Quellenangaben aus dem Jahr 2008. ... Als Aufsatzsammlung von Wissenschaftlern für Wissenschaftler will das Buch wiederum zu grundsätzlich und umfassend sein. ... Ein aktuelles und spannendes Thema ...“ (in: Transkript, March/2010, Issue 3, S. 67)

• Inst. Immunologie, Universität Witten/Herdecke, Witten, Germany

  Thomas Dittmar, Kurt S. Zanker

Policies and ethics