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  • © 2011

Medaka

A Model for Organogenesis, Human Disease, and Evolution

  • The first book to cover the expanding research on medaka

  • Describes recent progress in the field and provides a good introduction of this fish system along with information on the long history of medaka in Japanese culture and science

  • Biological and genome resources are listed with accessible web sites, especially helpful for new researchers in the field

  • Includes supplementary material: sn.pub/extras

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eBook USD 169.00
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Softcover Book USD 219.99
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Hardcover Book USD 219.99
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Table of contents (24 chapters)

  1. Front Matter

    Pages i-xvii
  2. Genomics, Genetics, and Resources

    1. Front Matter

      Pages 17-17
    2. Chromatin-Associated Periodicity in Genetic Variation Downstream of Transcriptional Start Sites

      • Shin Sasaki, Cecilia C. Mello, Atsuko Shimada, Yoichiro Nakatani, Shin-ichi Hashimoto, Masako Ogawa et al.
      Pages 39-47
    3. Transposable Elements Tol1 and Tol2

      • Akihiko Koga
      Pages 49-58
  3. Organogenesis and Disease Models

    1. Front Matter

      Pages 79-79
    2. Medaka Bone Development

      • Akira Kudo
      Pages 81-93
    3. Anatomical Atlas of Blood VascularSystem of Medaka

      • Sumio Isogai, Misato Fujita
      Pages 95-109
    4. p53-Deficient Medaka Created by TILLING

      • Yoshihito Taniguchi
      Pages 157-172
    5. Medaka Spontaneous Mutants for Body Coloration

      • Shoji Fukamachi
      Pages 173-184
    6. Craniofacial Traits

      • Minori Shinya
      Pages 185-199
  4. Germ Cells, Sex Determination, and Reproduction

    1. Front Matter

      Pages 217-217
    2. Function of the Medaka Male Sex-Determining Gene

      • Manfred Schartl
      Pages 241-253

About this book

Oryzias latipes, known as medaka, is a model organism from East Asia. Breeding of this small, egg-laying freshwater teleost fish has long been popular among hobbyists in Japan. Now, as biological science has entered the genome era, the medaka provides significant advantages that make it one of the most valuable vertebrate models: a large collection of spontaneous mutants collected over a century, the presence of highly polymorphic inbred lines established over decades, and a recently completed genome sequence. This book is the first comprehensive monograph to cover a variety of medaka research. It opens with a historical view of medaka, followed by a series of research topics in the four major areas where the medaka is increasingly important: genomics, genetics, and resources; organogenesis and disease models; germ cells, sex determination, and reproduction; and evolution. Readers will find state-of-the-art information on medaka genetics and genomics such as the first isolation of active transposons in vertebrates, the influence of chromatin structure on sequence variation, fine QTL analysis, and versatile mutants as human disease models.

Reviews

“In view of the abundance of the topics treated in this volume, the state-of-the-art information on Medaka genetics and genomics, the meaningful figures and diagrams (many are suitable for teachings), and the wealth of references, this volume is surely a ‘must’ for those working with this model organism, but it is also recommended to all researches interested in fish biology.” (Hartmut Greven, Bulletin of Fish Biology, Vol. 15, 2015)

Editors and Affiliations

  • Laboratory of Bioresources, National Institute for Basic Biology, Okazaki, Japan

    Kiyoshi Naruse

  • Laboratory of Molecular Genetics for Reproduction, National Institute for Basic Biology, Okazaki, Japan

    Minoru Tanaka

  • Department of Biological Sciences Graduate School of Science, The University of Tokyo, Tokyo, Japan

    Hiroyuki Takeda

Bibliographic Information

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access