New Trends in the Molecular and Biological Basis for Clinical Oncology

Newly developed molecular target anticancer drugs have shown remarkable efficacy even in the treatment of intractable cancers such as hepatoma and renal cell carcinoma. As cancer research is becoming a multidisciplinary endeavor, close cooperation across the basic, translational, and clinical research fields holds the promise of further advances in cancer therapeutics. This book sets forth new strategies for development: cancer therapy targeting receptor tyrosine kinases with clinical utilization of new signaling regulations; interaction between cancer progression and extracellular environments such as inflammatory cytokines and the extracellular matrix; and investigation of biomarkers for personalized cancer therapy, with microarray analysis and pharmacogenomics technology. These and other findings from the latest investigations into cancer cell biology and therapeutics make this book an invaluable source for investigators in both the clinical and basic cancer research fields.

• Cancer Screening
• angiogenesis
• cancer
• cancer therapy
• carcinoma
• cell
• cell biology
• cytokine
• cytokines
• genome
• genomics
• laser
• microarray
• renal cell carcinoma
• tumor

• Department of Oral Pathology and Diagnosis, Showa University School of Dentistry, Tokyo, Japan

  Tetsuhiko Tachikawa

• Department of Microbiology, Showa University School of Pharmaceutical Sciences, Tokyo, Japan

  Kiyoshi Nose

• Institute of Molecular Oncology, Showa University, Tokyo, Japan

  Tohru Ohmori

• Division of Allergology and Respiratory Medicine, Department of Internal Medicine, Showa University School of Medicine, Tokyo, Japan

  Mitsuru Adachi

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