Brain Tumor

1. Front Matter

   Pages II-XIV

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2. Reevaluation of Classification and Grading of Brain Tumors

   1. Front Matter

      Pages 1-1

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   2. General Considerations and Statistics

      1. Histopathological Classification of Brain Tumors According to the Revised WHO Classification: Current State and Perspectives

         • Wolfgang Wechsler, Guido Reifenberger

         Pages 3-20

      2. Histological Aspects of Certain Benign Brain Tumors: Review of Current Topics

         • Asao Hirano, Kazuhiko Sugiyama, Josefina F. Llena

         Pages 21-27

      3. The Statistical Analysis of Prognostic Factors for Brain Tumors

         • Kazuhiro Nomura, Naohito Yamaguchi, Show Watanabe

         Pages 29-38

   3. Glial Tumors

      1. Evaluation of Histological Grading Systems of Astrocytic Tumors

         • Nobuyuki Kawano, Hidehiro Oka, Tomonari Suwa, Kenzoh Yada

         Pages 39-44

      2. Histological and Radioimaging Study of Malignant Change in Low-Grade Astrocytoma

         • Masaru Tamura, Takashi Shibasaki, Satoru Horikoshi, Akira Zama, Hideyuki Kurihara, Nobuo Ono et al.

         Pages 45-49

      3. Clinicopathological Study of Mixed Oligoastrocytoma

         • Yukie Shimada, Osami Kubo, Yasuhiko Tajika, Hirohumi Hiyama, Shouko Atuji, Kintomo Takakura

         Pages 51-60

      4. Metallothionein in Gliomas

         • Hisashi Nitta, Yutaka Hayashi, Yoshie Okada, Osamu Tachibana, Masanao Mouri, Tetsumori Yamashima et al.

         Pages 61-67

   4. Meningioma

      1. Histological Grading of Meningioma Based on MIB-1 Immunoreactivity

         • Junko Hirato, Yoichi Nakazato, Masafumi Hirato

         Pages 69-78

      2. Incidental Meningiomas in Autopsy Cases in Computed Tomography and Magnetic Resonance Imaging Era

         • Kazuhiko Sugiyama, Asao Hirano, Josefina F. Llena, Tohru Uozumi, Kaoru Kurisu, Kunyu Harada et al.

         Pages 79-88

      3. Clinicopathological Study of Malignant Meningiomas

         • Junichi Mizuno, Hiroshi Nakagawa, Kazuo Hara, Yoshio Hashizume

         Pages 89-99

3. Dynamic aspects of the Biology of Brain Tumor Cells

   1. Front Matter

      Pages 101-101

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   2. Cell Motility

      1. Expression of L1CAM in Brain Tumors: Immunohistochemical Study Using Anti-L1CAM Antibodies

         • Shuichi Izumoto, Norio Arita, Takanori Ohnishi, Shoju Hiraga, Takuyu Taki, Toru Hayakawa

         Pages 103-107

      2. Expression and Biological Functions of L1 Cell Adhesion Molecule in Malignant Glioma Cells

         • Takanori Ohnishi, Shuichi Izumoto, Norio Arita, Shoju Hiraga, Takuyu Taki, Toru Hayakawa

         Pages 109-118

      3. The Role of Urokinase-Type Plasminogen Activator in the Invasion and Proliferation of Malignant Brain Tumors

         • Shingo Takano, Yoshihiko Yoshii, Tadao Nose, Barry Landau, Steven Brem

         Pages 119-125

   3. Cell Kinetics

      1. Stemline Study Based on the Nuclear Characterization and Image Cytometry in Resected Brain Tumors

         • Yoshihiko Yoshii, Atsushi Saito, Koji Tsuboi, Shingo Takano, Yoji Komatsu, Hideo Tsurushima et al.

         Pages 127-140

      2. Efficiency of Glioma Score in Glioma Patients Using Proliferating Potential with MIB-1 Monoclonal Antibody

         • Tatsuhiro Maeda, Kazuhiko Saruta, Satoyuki Ito, Hiroki Sawa, Isamu Saito

         Pages 141-148

4. Molecular Neuro-Oncology and Its Impact on the Clinical Management of Brain Tumors

   1. Front Matter

      Pages 149-149

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   2. Molecular Biology and Genetics

      1. Molecular Analysis of Phosphorylated Tyrosine-Binding Proteins in the Transduction of Proliferation and Differentiation Signals

         • Kazuo Nagashima, Shinya Tanaka, Satoshi Ota, Hideki Hasegawa, Michiyuki Matsuda

         Pages 151-159

The title of this monograph, Brain Tumor Research and Therapy, is the name of the Conference itself, which had its inaugural meeting in the United States in 1975 andhas since progressed to the international scale. In Japan, the first conference ofits kind was organized by Dr. Takao Hoshino and me and was held at Nikko in 1980, hence its name, the Nikko Conference on Brain Tumor Research and Therapy. Though it started as a small, closed meeting, the conference has grown considerably, and in 1992 it was reorganized as the Japanese Conference on Brain Tumor Research and Therapy and was opened to all neurosurgeons and neuropathologists interested in the study of brain tumor problems and who are participating in this field. The main purpose of the Conference on Brain Tumor Research and Therapy is the candid and informed discussion of the most up-to-date developments in basic re­ search and clinical treatment of brain tumors. The 3rd Japanese Conference on Brain Tumor Research and Therapy was held at Nasu (Tochigi Prefecture), Japan, in No­ vember 1994. It was a great honor to welcome many distinguished guests from over­ seas who kindly attended each session and made valuable contributions.

• Grading
• brain
• brain tumor
• cancer
• cell
• central nervous system
• genetics
• glioma
• histocompatibility
• molecular genetics
• mutation
• nervous system
• oncology
• pathogenesis
• tumor

• Department of Neurosurgery, Dokkyo University School of Medicine, Mibu, Tochigi, Japan

  Masakatsu Nagai

Policies and ethics