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Birkhäuser

Poxviruses

  • Book
  • © 2007

Overview

Editors:
  1. Andrew A. Mercer

    1. Department of Microbiology, University of Otago, Dunedin, New Zealand

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    You can also search for this editor in PubMed   Google Scholar

  2. Axel Schmidt

    1. Faculty of Medicine, University Witten/Herdecke, Witten, Germany

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  3. Olaf Weber

    1. BAYER HEALTHCARE AG, Product-related Research, Wuppertal, Germany

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Comprehensive review of the poxvirus family
  • Emphasis on current developments
  • Highlights new applications for biomedical research
  • Includes supplementary material: sn.pub/extras

Part of the book series: Birkhäuser Advances in Infectious Diseases (BAID)

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Table of contents (21 chapters)

  1. Front Matter

    Pages i-xx
    Download chapter PDF

  2. Genus Orthopoxvirus: Vaccinia virus

    • Geoffrey L. Smith
    Pages 1-45

  3. Genus Orthopoxvirus: Variola virus

    • Inger K. Damon
    Pages 47-64

  4. Genus Orthopoxvirus: Monkeypox virus

    • Sandra Essbauer, Hermann Meyer
    Pages 65-73

  5. Genus Orthopoxvirus: Cowpox virus

    • Sandra Essbauer, Hermann Meyer
    Pages 75-88

  6. Genus Molluscipoxvirus

    • Joachim J. Bugert
    Pages 89-112

  7. Genus Yatapoxvirus

    • Geoffrey L. Smith
    Pages 113-125

  8. Genus Parapoxvirus

    • Stephen B. Fleming, Andrew A. Mercer
    Pages 127-165

  9. Genus Capripoxvirus

    • Adama Diallo, Gerrit J. Viljoen
    Pages 167-181

  10. Genus Leporipoxvirus

    • John W. Barrett, Grant McFadden
    Pages 183-201

  11. Genus Suipoxvirus

    • Gustavo A. Delhon, Edan R. Tulman, Claudio L. Afonso, Daniel L. Rock
    Pages 203-215

  12. Genus Avipoxvirus

    • David B. Boyle
    Pages 217-251

  13. Subfamily Entomopoxvirinae

    • Marie N. Becker, Richard W. Moyer
    Pages 253-271

  14. Immunomodulation by poxviruses

    • Steven H. Nazarian, Grant McFadden
    Pages 273-296

  15. Immunomodulation by inactivated Orf virus (ORFV) - therapeutic potential

    • Olaf Weber, Percy Knolle, Hans-Dieter Volk
    Pages 297-310

  16. Recombinant poxvirus vaccines in biomedical research

    • Barbara S. Schnierle, Yasemin Suezer, Gerd Sutter
    Pages 311-327

  17. Orthopoxvirus vaccines and vaccination

    • Lauren M. Handley, J. Paige Mackey, R. Mark Buller, Clifford J. Bellone
    Pages 329-353

  18. Poxvirus diagnostics

    • Martin Pfeffer, Hermann Meyer
    Pages 355-373

  19. Therapy of poxvirus infections

    • Robert Snoeck, Graciela Andrei, Erik De Clercq
    Pages 375-395

  20. Environmental resistance, disinfection, and sterilization of poxviruses

    • Friedrich v. Rheinbaben, Jürgen Gebel, Martin Exner, Axel Schmidt
    Pages 397-405
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Keywords

About this book

The study of poxviruses has a long and distinguished history that includes Jenner’s founding work on smallpox vaccination. In the more than 200 years since that time we have seen the remarkable eradication of smallpox. It is difficult to overstate the significance of that achievement. It not only removed a disease that must rate as one of humankind’s greatest scourges, but also demonstrated the effectiveness of the general principle of vacci- tion in our battles against disease. This book begins with a review of smallpox and its causative agent, Variola virus. The vaccine used in the successful smallpox eradication c- paign, vaccinia virus, is reviewed in the following chapter that describes its origin and its use as a vaccine, as well as the current understanding of the molecular biology and pathogenesis of this virus. Vaccinia virus is the most intensively studied poxvirus and the descriptions of the biology of this virus are relevant to all vertebrate poxviruses. The eradication ofsmallpox has drawn attention to the potential threat posed by other orthopoxviruses that infect humans, particularly Monkeypox virus. A description of this virus is given in the third chapter. Jenner’s ori- nal vaccine is believed to have been Cowpox virus and this virus is reviewed in the chapter by Essbauer and Meyer. Additional chapters are devoted to each of the recognized genera of the vertebrate poxviruses and a f- ther chapter describes the subfamily of poxviruses infecting invertebrates. Together these provide a comprehensive review of the poxvirus family.

Editors and Affiliations

  • Department of Microbiology, University of Otago, Dunedin, New Zealand

    Andrew A. Mercer

  • Faculty of Medicine, University Witten/Herdecke, Witten, Germany

    Axel Schmidt

  • BAYER HEALTHCARE AG, Product-related Research, Wuppertal, Germany

    Olaf Weber

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