Overview
- Editors:
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Leon P. Bignold
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University of Adelaide Dept. Pathology, Adelaide, Australia
- A concise compilation of current knowledge about tumor morphological abnormality
- Provides insight into molecular mechanisms of carcinogenesis
- Presents new targets for medical intervention
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Table of contents (15 chapters)
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- Leon P. Bignold, B. L. D. Coghlan, H. P. A. Jersmann
Pages 1-24
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- Bojan Drobic, Katherine L. Dunn, Paula S. Espino, James R. Davie
Pages 25-47
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- Sen Pathak, Asha S. Multani
Pages 49-64
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- Troy R. Durham, Elizabeth T. Snow
Pages 97-130
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- David I. Pattison, Michael J. Davies
Pages 131-157
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- Carmel Mothersill, C. B. Seymour
Pages 159-177
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- Karl Münger, Hiroyuki Hayakawa, Christine L. Nguyen, Nadja V. Melquiot, Anette Duensing, Stefan Duensing
Pages 179-199
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- Herman H. Cheung, Vinay Arora, Robert G. Korneluk
Pages 201-221
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- Jay Harper, Marsha A. Moses
Pages 223-268
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- Okio Hino, Toshiyuki Kobayashi, Kazuo Okimoto
Pages 269-292
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- Marianne Sowa, Benjamin J. Arthurs, Brian J. Estes, William F. Morgan
Pages 293-301
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- Stavroula Raptis, Bharati Bapat
Pages 303-320
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- William B. Coleman, Gregory J. Tsongalis
Pages 321-349
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Back Matter
Pages 363-376
About this book
This volume began with an invitation from the publishers to edit a volume of EXS on Cancer. This invitation undoubtedly derived from my articles in Cellular and Molecular Life Sciences in 2002 and 2003 on the relationships between the morphology, aetiology and pathogenesis of tumours, especially in relation to genetic instability. After many years of teaching the theories of c- cer in undergraduate medical school courses, it seemed to me that the variably chaotic histopathologic features of tumours parallel in some way, the variably unstable genomes of tumour cells, which were being discovered in the 1990s. Thus the title of the volume has come to include morphology, carcinogenesis and genetic instability. The invitation came while I was working with Herrn Dr. med. Hubertus Jersmann (MD Düsseldorf, PhD, now Senior Lecturer in Medicine of the University of Adelaide) and Professor Brian Coghlan (Emeritus Professor of German, the University of Adelaide), on the work of the nineteenth century cancer pathologists, especially David Paul von Hansemann (1858–1920). With the delivery of the manuscripts from the authors of the chapters, it became obvious that a background chapter for the volume could include some of the material which we had “uncovered” together. Because of this, chapter 1 is authored by the three of us, and the “new” material figures prominently.
Editors and Affiliations
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University of Adelaide Dept. Pathology, Adelaide, Australia
Leon P. Bignold
