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Birkhäuser

Antibiotics as Anti-Inflammatory and Immunomodulatory Agents

  • Book
  • © 2005

Overview

Editors:
  1. Bruce K. Rubin

    1. Department of Pediatrics School of Medicine, Wake Forest University, Winston-Salem, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Jun Tamaoki

    1. First Department of Medicine, Tokyo Women's Medical University, Tokyo, Japan

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    You can also search for this editor in PubMed   Google Scholar

  • International authorship
  • Covers basic research and clinical results

Part of the book series: Progress in Inflammation Research (PIR)

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-xiii
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  2. Basic research

    1. Effects of antibiotics on Pseudomonas aeruginosa virulence factors and quorum-sensing system

      • Kazuhiro Tateda, Theodore J. Standiford, Keizo Yamaguchi
      Pages 5-24

    2. Antibiotics, inflammation and its resolution: An overview

      • Michael J. Parnham
      Pages 27-47

    3. The cytoprotective interactions of antibiotics with human ciliated airway epithelium

      • Charles Feldman, Ronald Anderson
      Pages 49-63

    4. Chemotaxis

      • Jun-ichi Kadota
      Pages 65-75

    5. Cytokines

      • Hajime Takizawa
      Pages 77-86

    6. Antibacterial agents and the oxidative burst

      • Marie-Thérèse Labro
      Pages 87-106

    7. Immune system

      • Jun-ichi Kadota
      Pages 107-119

    8. Macrolides and mucus production

      • Kiyoshi Takeyama
      Pages 123-132

    9. Ion channel regulation

      • Jun Tamaoki
      Pages 133-144

  3. Clinical results

    1. The use of macrolides for treatment of diffuse panbronchiolitis

      • Arata Azuma, Shoji Kudoh
      Pages 147-165

    2. Macrolides in cystic fibrosis

      • Adam Jaffé, Andrew Bush
      Pages 167-191

    3. Macrolides and upper airway/sinus disease

      • Kazuhiko Takeuchi, Yuichi Majima, Qutayba Hamid
      Pages 193-203

    4. Benefits of macrolides in the treatment of asthma

      • Rose Jung, Mark H. Gotfried, Larry H. Danziger
      Pages 205-218

    5. Roles of macrolides in treatment of lung injury

      • Arata Azuma
      Pages 219-226

    6. Macrolides and cancer, arthritis and IBD

      • Keiichi Mikasa, Kei Kasahara, Eiji Kita
      Pages 227-245

    7. Anti-inflammatory properties of antibiotics other than macrolides

      • Bruce K. Rubin, Markus O. Henke, Axel Dalhoff
      Pages 247-267

  4. Back Matter

    Pages 269-278
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Keywords

About this book

Although the potential for immunomodulation has been recognized for many years there has been an explosion of data in this field with relevance especially to the treatment of chronic airway diseases. Most of the work in this field has been conducted by Japanese investigators but in the last decade there has been a body of work outside of Japan that supports and enhances these findings. The book covers basic research like effects on bacteria, anti-inflammatory and mucoregulatory effects, but also clinical results with up-to-date information for the use of such medications to potentially treat diseases as diverse as chronic airway diseases, arthritis, inflammatory bowel disease, and cancer.
The volume is intended for pulmonary physicians, researchers in inflammation research, and pharmaceutical companies interested in the development of such agents. It provides background information for the clinician as well as in depth exploration of cutting edge science.

Reviews

This concise and well-illustrated monograph contains much information of value to clinical immunologists and microbiologists engaged in research on the management and treatment of infectious diseases."

(Clinical Infectious Diseases)

Editors and Affiliations

  • Department of Pediatrics School of Medicine, Wake Forest University, Winston-Salem, USA

    Bruce K. Rubin

  • First Department of Medicine, Tokyo Women's Medical University, Tokyo, Japan

    Jun Tamaoki

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