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DNA Fingerprinting: State of the Science

  • Book
  • © 1993

Overview

Editors:
  1. S. D. J. Pena

    1. Núcleo de Genética Médica de Minas Gerais (GENE/MG), Belo Horizonte, Brazil

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  2. R. Chakraborty

    1. Genetics Center, University of Texas Health Science Center, Houston, USA

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  3. J. T. Epplen

    1. Molekulare Humangenetik, MA, Ruhr-Universität, Bochum, Germany

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  4. Alec J. Jeffreys

    1. Department of Genetics, University of Leicester, Leicester, England

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Part of the book series: Experientia Supplementum (EXS)

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Table of contents (46 chapters)

  1. Front Matter

    Pages i-xi
    Download chapter PDF

  2. Part I Basic Aspects of DNA Fingerprints: Genomic Organization, Dynamics and Variability of Tandemly Repeated DNA Sequences

    1. Brief introduction to human DNA fingerprinting

      • A. J. Jeffreys, S. D. J. Pena
      Pages 1-20

    2. Notes on the definition and nomenclature of tandemly repetitive DNA sequences

      • Diethard Tautz
      Pages 21-28

    3. On the essence of “meaningless” simple repetitive DNA in eukaryote genomes

      • C. Epplen, G. Melmer, I. Siedlaczck, F.-W. Schwaiger, W. Mäueler, J. T. Epplen
      Pages 29-45

    4. Detection, cloning, and distribution of minisatellites in some mammalian genomes

      • G. Vergnaud, D. Gauguier, J.-J. Schott, D. Lepetit, V. Lauthier, D. Mariat et al.
      Pages 47-57

    5. Frequency of restriction site polymorphisms in the region surrounding VNTR loci

      • I. Balazs, J. Neuweiler, L. Perlee, J. Venturini
      Pages 59-62

    6. Human VNTR mutation and sex

      • B. Olaisen, M. Bekkemoen, P. Hoff-Olsen, P. Gill
      Pages 63-69

    7. Variation of minisatellites in chemically induced mutagenesis and in gene amplification

      • P. Vagnarelli, E. Giulotto, P. Fattorini, E. Mucciolo, M. Bensi, L. Tessera et al.
      Pages 71-77

    8. Iterons of stringently controlled plasmids and DNA fingerprinting

      • K. J. Huebscher, G. Dolf, J. Frey
      Pages 79-85

    9. Towards covering immunological genes with highly informative markers: A trans-species approach

      • J. Buitkamp, W. Schwaiger, C. Epplen, M. Gomolka, E. Weyers, J. T. Epplen
      Pages 87-102

    10. Arbitrary primed PCR fingerprinting of RNA applied to mapping differentially expressed genes

      • M. McClelland, K. Chada, J. Welsh, D. Ralph
      Pages 103-115

    11. Rapid analysis of PCR components and products by acidic non-gel capillary electrophoresis

      • M. J. Pearce, N. D. Watson
      Pages 117-124

  3. Part II Application of DNA Fingerprinting to the Study of Human Populations

    1. Minisatellite variant repeat mapping: Application to DNA typing and mutation analysis

      • A. J. Jeffreys, D. G. Monckton, K. Tamaki, D. L. Neil, J. A. L. Armour, A. MacLeod et al.
      Pages 125-139

    2. Microsatellites and disease: A new paradigm

      • K. Wrogemann, V. Biancalana, D. Devys, G. Imbert, Y. Trottier, J.-L. Mandel
      Pages 141-152

    3. A unified approach to study hypervariable polymorphisms: Statistical considerations of determining relatedness and population distances

      • R. Chakraborty, L. Jin
      Pages 153-175

    4. The forensic significance of various reference population databases for estimating the rarity of variable number of tandem repeat (VNTR) loci profiles

      • B. Budowle, K. L. Monson
      Pages 177-191

    5. Population genetics of 14 ethnic groups using phenotypic data from VNTR loci

      • I. Balazs
      Pages 193-210

    6. Genetic variation among the Mapuche Indians from the Patagonian region of Argentina: Mitochondrial DNA sequence variation and allele frequencies of several nuclear genes

      • C. Ginther, D. Corach, G. A. Penacino, J. A. Rey, F. R. Carnese, M. H. Hutz et al.
      Pages 211-219

    7. Microsatellite and HLA class II oligonucleotide typing in a population of Yanomami Indians

      • L. Roewer, M. Nagy, P. Schmidt, J. T. Epplen, G. Herzog-Schröder
      Pages 221-230

    8. Isérables: A Bedouin village in Switzerland?

      • C. Brandt-Casadevall, N. Dimo-Simonin, A. Sutter, H.-R. Gujer
      Pages 231-235
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Keywords

About this book

DNA fingerprinting had a well-defined birthday. In the March 7, 1985 issue of Nature, Alec Jeffreys and coworkers described the first develop­ ment ofmu1tilocus probes capable of simultaneously revealing hypervari­ ability at many loci in the human genome and called the procedure DNA fingerprinting. It was a royal birth in the best British tradition. In a few months the emerging technique had permitted the denouement of hith­ erto insoluble immigration and paternity disputes and was already heralded as a major revolution in forensic sciences. In the next year (October, 1986) DNA fingerprinting made a dramatic entree in criminal investigations with the Enderby murder case, whose story eventually was turned into a best-selling book ("The Blooding" by Joseph Wambaugh). Today DNA typing systems are routinely used in public and commercial forensic laboratories in at least 25 different countries and have replaced conventional protein markers as the methods of choice for solving paternity disputes and criminal cases. Moreover, DNA fingerprinting has emerged as a new domain of intense scientific activity, with myriad applications in just about every imaginable territory of life sciences. The Second International Conference on DNA Fingerprinting, which was held in Belo Horizonte, Brazil in November of 1992, was a clear proof of this.

Editors and Affiliations

  • Núcleo de Genética Médica de Minas Gerais (GENE/MG), Belo Horizonte, Brazil

    S. D. J. Pena

  • Genetics Center, University of Texas Health Science Center, Houston, USA

    R. Chakraborty

  • Molekulare Humangenetik, MA, Ruhr-Universität, Bochum, Germany

    J. T. Epplen

  • Department of Genetics, University of Leicester, Leicester, England

    Alec J. Jeffreys

Bibliographic Information

  • Book Title: DNA Fingerprinting: State of the Science

  • Editors: S. D. J. Pena, R. Chakraborty, J. T. Epplen, Alec J. Jeffreys

  • Series Title: Experientia Supplementum

  • DOI: https://doi.org/10.1007/978-3-0348-8583-6

  • Publisher: Birkhäuser Basel

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Basel AG 1993

  • Softcover ISBN: 978-3-7643-2906-8Published: 01 July 1993

  • eBook ISBN: 978-3-0348-8583-6Published: 07 March 2013

  • Series ISSN: 1664-431X

  • Series E-ISSN: 2504-3692

  • Edition Number: 1

  • Number of Pages: XI, 468

  • Topics: Forensic Medicine, Science, Humanities and Social Sciences, multidisciplinary

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