Stereotactic and Functional Neurosurgery

1. Front Matter

   Pages i-x

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2. The Birth of Human Stereotactic Surgery

   • Philip L. Gildenberg

   Pages 1-4

3. Functional Neurosurgery in Parkinson’s Disease: A Long Journey from Destruction Over Modulation Towards Restoration

   • Guido Nikkhah, Gustavo Adolpho Carvalho, Marcus Pinsker

   Pages 5-11

4. Improving MRT Image Quality in Patients with Movement Disorders

   • Elisabeth Schültke, Norbert Nanko, Marcus Pinsker, Michael Katzev, Alexandra Sebastian, Bernd Feige et al.

   Pages 13-17

5. STN Stimulation in General Anaesthesia: Evidence Beyond ‘Evidence-Based Medicine’

   • Christian K. E. Moll, Sebastian Payer, Alessandro Gulberti, Andrew Sharrott, Simone Zittel, Kai Boelmans et al.

   Pages 19-25

6. The Impact of Multichannel Microelectrode Recording (MER) in Deep Brain Stimulation of the Basal Ganglia

   • Thomas M. Kinfe, Jan Vesper

   Pages 27-33

7. A Comparison Between Stereotactic Targeting Methods of the Subthalamic Nucleus in Cases with Parkinson’s Disease

   • Ali Savas, Melih Bozkurt, Cenk Akbostancı

   Pages 35-41

8. Behind the Screen: Pseudobulbar Symptoms After Deep Brain Stimulation

   • Florian Amtage, Johann Lambeck, Sebastian Rutsch, Thomas Prokop, Marcus Pinsker, Michel Rijntjes

   Pages 43-46

9. Psychiatric Side-Effects of Bilateral Deep Brain Stimulation for Movement Disorders

   • Marcus Pinsker, Florian Amtage, Mathias Berger, Guido Nikkhah, Ludger Tebartz van Elst

   Pages 47-51

10. Active Stimulation Site of Nucleus Accumbens Deep Brain Stimulation in Obsessive–Compulsive Disorder Is Localized in the Ventral Internal Capsule

    • Pepijn van den Munckhof, D. Andries Bosch, Mariska H. M. Mantione, Martijn Figee, Damiaan A. J. P. Denys, P. Richard Schuurman

    Pages 53-59

11. Functional Neurosurgery for Secondary Dystonia: Indications and Long-Term Results

    • Jairo Alberto Espinoza Martinez, Oscar Andres Escobar Vidarte, Gabriel Arango Uribe

    Pages 61-66

12. Deep Brain Stimulation of the Ventrolateral Thalamic Base and Posterior Subthalamic Area in Dystonic Head Tremor

    • Carsten Buhmann, Christian K. E. Moll, Simone Zittel, Alexander Münchau, Andreas K. Engel, Wolfgang Hamel

    Pages 67-72

13. Intra-operative Transdural Electric Stimulation in Awake Patient: Target Refining for Motor Cortex Stimulation

    • Manoel Jacobsen Teixeira, Daniel Ciampi de Andrade, Erich Talamoni Fonoff

    Pages 73-78

14. Restorative Strategies for the Dopaminergic Nigrostriatal Projection Pathway

    • Guido Nikkhah

    Pages 79-85

15. Some Recent Trends and Further Promising Directions in Functional Neurosurgery

    • Travis S. Tierney, Tejas Sankar, Andres M. Lozano

    Pages 87-92

16. Impact of Automated Hotspot Detection for 18FET PET-Guided Stereotactic Biopsy

    • Thomas Reithmeier, Joacir Cordeiro, Michael Mix, Michael Trippel, Christoph Rottenburger, Guido Nikkhah

    Pages 93-99

17. Interstitial Radiosurgery with Iodine-125 Seeds in the Treatment of Brain Metastases, Glial Tumours and Benign Intracranial Lesions

    • Michael Trippel, Thomas Reithmeier, Guido Nikkhah

    Pages 101-106

18. Back Matter

    Pages 107-112

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Since its introduction about sixty years ago, stereotactic and functional neurosurgery has evolved into a fascinating and interdisciplinary endeavor that combines modern neurosurgery, neurobiology, and neuroimaging with innovative diagnostic and treatment strategies. In this collection, acknowledged experts from Europe and North and South America present their scientific and clinical experience in stereotactic and functional neurosurgery for movement disorders and brain tumors. The contributions present a wide range from the beginnings of human stereotactic neurosurgery to the most modern molecular and restorative strategies to treat diseases of the human nervous system. They clearly demonstrate that the discipline is still young and dynamic with alternative and sometimes competing strategies whose evaluation is underway. They also document that operative lesioning techniques such as thalamotomies, though still chosen under certain circumstances, have been succeeded by novel neuromodulation techniques such as deep brain stimulation in the great majority of clinical cases.

• functional neurosurgery
• movement disorders
• stereotactic neurosurgery
• tumors

• , Neurosurgical Clinic, University Hospital Erlangen, Erlangen, Germany

  Guido Nikkhah

• Department of Neurosurgery, Division of Stereotactic and Functional, University Medical Center Freiburg, Freiburg, Germany

  Marcus Pinsker

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