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Human Gene Therapy: Current Opportunities and Future Trends

  • Conference proceedings
  • © 2003

Overview

Editors:
  1. Gabor M. Rubanyi

    1. Berlex Biosciences, Richmond, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Seppo Ylä-Herttuala

    1. Department of Molecular Medicine, A.I. Virtanen Institute, University of Kuopio, Finland

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Ernst Schering Foundation Symposium Proceedings (SCHERING FOUND, volume 43)

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Table of contents (14 papers)

  1. Front Matter

    Pages I-XV
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  2. The Future of Gene Therapy

    1. The Future of Gene Therapy

      • G. J. Nabel
      Pages 1-16

  3. Cardiovascular Diseases

    1. Front Matter

      Pages 17-17
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    2. Angiogenesis Clinical Trials

      • S. Ylä-Herttuala
      Pages 19-23

    3. AAV Vectors, the Future Workhorse of Human Gene Therapy

      • R. J. Samulski
      Pages 25-40

    4. Nonviral Vectors for Cardiovascular Gene Delivery

      • J. A. Wolff, H. Herweijer
      Pages 41-59

    5. Gene Therapy for Coronary Artery Disease: Preclinical and Initial Clinical Results with Intracoronary Administration of Ad5FGF-4

      • M. W. Watkins, G. M. Rubanyi
      Pages 61-78

  4. Cancer

    1. Front Matter

      Pages 79-79
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    2. Cancer Gene Therapy: Present Status and Future Directions

      • G. J. Nabel
      Pages 81-88

    3. Oncolytic Virotherapy as a Novel Treatment Platform for Cancer

      • D. Kirn
      Pages 89-105

    4. Adenovirus Retargeting and Systemic Delivery

      • L. W. Seymour, K. D. Fisher, N. K. Green, S. J. Hale, M. Lyons, V. Mautner et al.
      Pages 107-114

  5. CNS Diseases

    1. Front Matter

      Pages 115-115
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    2. CNS Diseases Amenable to Gene Therapy

      • H. J. Federoff
      Pages 117-158

    3. Molecular Therapies for the Nervous System and Muscle

      • G. Karpati
      Pages 159-178

    4. Lentivirus: A Vector for Nervous System Applications

      • S. M. Kingsman
      Pages 179-207

  6. Novel Technologies

    1. Front Matter

      Pages 209-209
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    2. Endothelial Progenitor Cells for Neovascularization

      • T. Asahara
      Pages 211-216

    3. Therapeutic Aptamers and Antidotes: A Novel Approach to Safer Drug Design

      • B. A. Sullenger, R. R. White, C. P. Rusconi
      Pages 217-223

    4. Plasmid-Based Gene Transfer and Antiprogestin-Controllable Transgene Expression

      • J. L. Nordstrom
      Pages 225-244

  7. Back Matter

    Pages 245-256
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Keywords

About this book

Advances in genetics, molecular biology and gene delivery technologies in recent years have led to new gene therapy strategies for treatment of a variety of diseases. This book gives a comprehensive overview of the present status and future directions of gene delivery systems and therapeutic strategies for the clinical application of gene therapy in cancer, cardiovascular and central nervous system diseases. Stem cell-based therapies and gene expression regulatory systems as novel platform technologies for various gene therapy applications are also discussed. Leading experts give excellent overviews of basic molecular aspects and clinical applications in this new emerging biomedical field.

Editors and Affiliations

  • Berlex Biosciences, Richmond, USA

    Gabor M. Rubanyi

  • Department of Molecular Medicine, A.I. Virtanen Institute, University of Kuopio, Finland

    Seppo Ylä-Herttuala

Bibliographic Information

  • Book Title: Human Gene Therapy: Current Opportunities and Future Trends

  • Editors: Gabor M. Rubanyi, Seppo Ylä-Herttuala

  • Series Title: Ernst Schering Foundation Symposium Proceedings

  • DOI: https://doi.org/10.1007/978-3-662-05352-2

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2003

  • Hardcover ISBN: 978-3-540-00413-4Published: 14 July 2003

  • Softcover ISBN: 978-3-662-05354-6Published: 22 December 2012

  • eBook ISBN: 978-3-662-05352-2Published: 17 April 2013

  • Series ISSN: 0947-6075

  • Edition Number: 1

  • Number of Pages: XV, 256

  • Topics: Human Genetics, Cancer Research, Oncology, Neurology, Molecular Medicine, Virology

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