Biologic Rhythms in Clinical and Laboratory Medicine

1. Front Matter

   Pages I-XVIII

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2. Basic Concepts

   1. Biologic Rhythms from Biblical to Modern Times. A Preface

      • Y. Touitou, E. Haus

      Pages 1-5

   2. Principles of Clinical Chronobiology

      • E. Haus, Y. Touitou

      Pages 6-34

3. Mechanisms of Rhythms

   1. Cellular and Molecular Aspects of Circadian Oscillators: Models and Mechanisms for Biological Timekeeping

      • L. N. Edmunds Jr.

      Pages 35-54

   2. The Suprachiasmatic Nucleus and Other Pacemakers

      • W. J. Rietveld

      Pages 55-64

   3. Molecular and Genetic Aspects of Chronobiology

      • D. J. Lakatua

      Pages 65-77

   4. Seasonal and Daily Control of Enzyme Synthesis and Activity by Circadian Clocks

      • O. Queiroz, C. Queiroz-Claret

      Pages 78-89

4. Data Processing

   1. Data Processing in Chronobiological Studies

      • J. De Prins, B. Hecquet

      Pages 90-113

5. Pharmacology and Toxicology

   1. Chronopharmacology

      • B. Bruguerolle

      Pages 114-137

   2. Chronotoxicology

      • J. Cambar, B. L’Azou, J. C. Cal

      Pages 138-150

   3. Rhythms in Drug-Induced Teratogenesis

      • I. Sauerbier

      Pages 151-157

6. Child Development and Aging

   1. Chronobiology of Pregnancy and the Perinatal Time Span

      • P. J. Meis

      Pages 158-166

   2. Patterns of Growth Hormone Release During Childhood and Adolescent Development in the Human

      • A. D. Rogol

      Pages 167-178

   3. Rhythms in Biochemical Variables Related to Bone and Their Regulating Hormones

      • M. E. Markowitz

      Pages 179-187

   4. Biological Rhythms and Aging

      • Y. Touitou, E. Haus

      Pages 188-207

7. Physical and Mental Performance

   1. Chronobiology of Mental Performance

      • T. H. Monk

      Pages 208-213

   2. Biological, Behavioral and Intellectual Activity Rhythms of the Child During Its Development in Different Educational Environments

      • H. Montagner, G. De Roquefeuil, M. Djakovic

      Pages 214-229

   3. Chronobiology of Physical Performance and Sports Medicine

      • C. M. Winget, M. R. I. Soliman, D. C. Holley, J. S. Meylor

      Pages 230-242

8. Shift Work and Transmeridian Flights

   1. Night and Shift Work and Transmeridian and Space Flights

      • A. E. Reinberg, M. H. Smolensky

      Pages 243-255

9. Sleep

   1. Chronobiology of Human Sleep and Sleep Disorders

      • B. Hayes, C. A. Czeisler

      Pages 256-264

Everyone has heard of nature's "biological clocks", the phenomenon of periodic activity in plants, animals and humans. But what does chronobiology have to do with modern medicine?
This book presents in a concise but comprehensive fashion the basic principles of chronobiology and their application to clinical medicine.
The chapters are written by specialists in the field; they summarize the physiology, pathophysiology and pathology of the human time structure and outline the application of chronobiologic principles and techniques for diagnosis and treatment.

• Biologic Rhythms
• Biorhythmus
• Chronobiology
• Clinical Medicine
• Laboratory Medicine
• biology
• pathophysiology
• physiology

• Faculté de Médecine Pitié-Salpétrière, Laboratoire de Biochimie Médicale, Paris Cedex 13, France

  Yvan Touitou

• Department of Laboratory Medicine and Pathology, University of Minnesota, St.Paul, USA

  Erhard Haus

• Department of Anatomic and Clinical Pathology, St. Paul-Ramsey Medical Center, St.Paul, USA

  Erhard Haus

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