Psychotropic Agents

1. Front Matter

   Pages I-XXVI

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2. Anxiolytics

   1. Front Matter

      Pages 1-1

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   2. The Chemistry of Anxiolytics

      • L. H. Sternbach

      Pages 3-12

   3. General Pharmacology and Neuropharmacology of Benzodiazepine Derivatives

      • W. Haefely, L. Pieri, P. Polc, R. Schaffner

      Pages 13-262

   4. General Pharmacology and Neuropharmacology of Propanediol Carbamates

      • W. Haefely, R. Schaffner, P. Polc, L. Pieri

      Pages 263-283

   5. Behavioral Pharmacology of Anxiolytics

      • P. B. Dews

      Pages 285-292

   6. Biochemical Effects of Anxiolytics

      • C. Braestrup

      Pages 293-319

   7. Pharmacokinetics and Metabolism of Anxiolytics

      • S. A. Kaplan, M. L. Jack

      Pages 321-358

   8. Toxicology and Side-Effects of Anxiolytics

      • L. R. Hines

      Pages 359-393

   9. Dependence-Producing Effects of Anxiolytics

      • T. Yanagita

      Pages 395-406

3. Gerontopsychopharmacological Agents

   1. Front Matter

      Pages 407-407

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   2. Chemistry of Gerontopsychopharmacologic Agents

      • H. Hauth

      Pages 409-434

   3. Pharmacologic Approaches to Gerontopsychiatry

      • D. M. Loew, J. M. Vigouret

      Pages 436-459

   4. Experimental Behavioral Pharmacology of Gerontopsychopharmacological Agents

      • C. Giurgea, G. Greindl, S. Preat

      Pages 461-492

   5. Cerebrovascular Agents in Gerontopsychopharmacotherapy

      • F. Hoffmeister, S. Kazda, F. Seuter

      Pages 493-532

   6. Biochemical Effects of Gerontopsychopharmacological Agents

      • S. Hoyer

      Pages 533-542

4. Psychomotor Stimulants

   1. Front Matter

      Pages 543-543

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   2. The Pharmacological Profile of Some Psychomotor Stimulant Drugs Including Chemical, Neurophysiological, Biochemical, and Toxicological Aspects

      • S. Garattini, R. Samanin

      Pages 545-586

   3. The Behavioral Pharmacology of Psychomotor Stimulant Drugs

      • C. R. Schuster

      Pages 587-605

   4. The Dependence-Producing Properties of Psychomotor Stimulants

      • J. E. Villarreal, L. A. Salazar

      Pages 607-635

This second volume continues the description of the psychotropic agents and discusses anxiolytics, gerontopsychopharmacological agents, and psychomotor stimulants. Of these groups of substances, most of this volume has been devoted to anxiolytics as the authors have endeavored to convey as complete a picture as possible. The editors are of the opinion that particular attention should be given to anxiolytics with regard to their range of administration as this is the most frequently prescribed group of psychotropic drugs. In contrast to neuroleptics and thymoleptics, anxiolytics are a class of psychotropic drugs whose therapeutic effect can be recognized in animal experiments to some extent. This, together with the analysis of the biochemical mechanisms of their actions, permits a better understanding of material processes in the brain accompanying the emotions: anxiety and tension. For the first time in the history of the Handbook the editors have devoted a whole chapter to gerontopsychopharmacological agents. In doing so they are also aware of the risk they are taking, at least from a pharmacological point of view, as gerontopsychopharmacological agents are an insufficiently defined and extremely heterogeneous group of substances. The only denominator the various subgroups of these agents have in common is that they are given in cases of dysfunctions, disorders, and diseases of the brain occurring mainly in the elderly.

• 1,4-Benzodiazepin
• Acetylcholin
• Histamin
• Hormone
• Hypothalamus
• Prostaglandin
• Respiration
• Serotonin
• Xanthin
• chemistry
• neurotransmitter
• pharmacodynamics
• pharmacokinetics
• pharmacology
• toxicology

• Institut für Pharmakologie, Bayer AG, Wuppertal 1, Germany

  F. Hoffmeister

• Institut für Arzneimittel des Bundesgesundheitsamtes, Berlin 30, Germany

  G. Stille

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