Prostate Cancer

1. Front Matter

   Pages I-XII

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2. Pathology and Molecular Biology of Prostate Cancer

   1. Front Matter

      Pages 1-1

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   2. Morphogenetic Aspects of Prostate Cancer

      • H. Bonkhoff

      Pages 3-12

   3. Cytogenetics of Prostate Cancer

      • L. Bubendorf

      Pages 13-23

   4. Molecular Dissection of the Prostate Cancer Genome

      • V. Srikantan, S. Srivastava

      Pages 25-40

   5. Diagnosis and Clinical Significance of Prostatic Intraepithelial Neoplasia

      • V. Ravery, L. Boccon-Gibod

      Pages 41-46

3. Diagnosis and Staging of Prostate Cancer

   1. Front Matter

      Pages 47-47

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   2. Prostate Biopsy — When, How, and When to Repeat?

      • W. Höltl

      Pages 49-53

   3. Molecular Forms of Prostate-Specific Antigen for Prostate Cancer Detection

      • B. Djavan, M. K. Brawer, M. Marberger

      Pages 55-65

   4. Clinical and Pathohistological Prognosticators

      • H. Huland, M. Graefen, A. Haese, P. G. Hammerer, J. Palisaar, U. Pichlmeier et al.

      Pages 67-75

   5. Preoperative Staging

      • P. Hammerer, M. Graefen, A. Haese, J. Palisaar, J. Noldus, S. Fernandez et al.

      Pages 77-90

   6. Preoperative Staging of Prostate Cancer: The Role of Molecular Markers

      • J. W. Moul, A. S. Merseburger

      Pages 91-100

   7. Preoperative Imaging Techniques in Prostate Cancer

      • R. Hofmann, A. Heidenreich, S. Wille, Z. Varga, R. V. Knobloch

      Pages 101-112

   8. Extended Pelvic Lymphadenectomy in Clinically Localized Prostate Cancer: High Frequency of Lymph Node Metastases

      • A. Heidenreich, Z. Varga, R. V. Knobloch, D. Brandt, R. Hofmann

      Pages 113-124

4. Operative Therapy of Clinically Localized Prostate Cancer

   1. Front Matter

      Pages 125-125

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   2. Anatomy: Surgical Aspects

      • R. Hofmann

      Pages 127-135

   3. Extended Pelvic Lymphadenectomy

      • R. Hofmann

      Pages 137-140

   4. Radical Ascending Retropubic Prostatectomy

      • R. Hofmann

      Pages 141-143

   5. Radical Descending Retropubic Prostatectomy

      • R. Hofmann

      Pages 145-148

   6. Radical Retropubic Nerve Sparing Prostatectomy

      • H. Huland, R. Hofmann

      Pages 149-156

Prostate cancer is not only the most common genitourinary tumor but, accord­ ing to the tumor registry of Munich, the male tumor with the highest inci­ dence. The wide range of information concerning this important disease has been dealt with comprehensively. In a time when interested urologists can surf in the internet to find an article they are looking for, they usually get lost because of the flood of papers covering the same subject. Furthermore, they are still alone in deciding which scientific contribution to believe and which will serve their patients best. A well-edited book such as this, however, provi­ des quick access to all pertinent questions. These renowned authors have taken on the responsibility of writing a balanced report and producing a sort of a guideline, i. e. , a diagnostic or therapeutic standard. The editors are to be congratulated on mastering such a formidable task, bringing together the leading names in prostate cancer to present their views on all the questions one might have about this disease. I trust that this book will serve urologists in practice and their patients well. J. E. Altwein Miinchen Contents Pathology and Molecular Biology of Prostate Cancer 1 Morphogenetic Aspects of Prostate Cancer H. Bonkhoff . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2 Cytogenetics of Prostate Cancer L. Bubendorf . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 3 Molecular Dissection of the Prostate Cancer Genome V. Srikantan, S. Srivastava . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 Diagnosis and Clinical Significance of Prostatic 4 Intraepithelial Neoplasia V. Ravery, L. Boccon-Gibod . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

• Staging
• anatomy
• biopsy
• cancer
• hormones
• imaging techniques
• implant
• incontinence
• molecular biology
• pathology
• prostate
• prostate cancer
• prostatectomy
• quality of life
• surgery

From the reviews:

"The authors take the challenge through the chapters and the different most recent references of covering the subject from diagnosis to treatment of both localized and invasive cancer. … Through out the chapters, one can find accurate information dealing with prostate cancer that will be of crucial help in daily practice. This -book- appears to be an appropriate hand book for the therapist in charge of prostate cancer; mainly the urologist but also the radiation therapist." (B Mathantu and J de Leval, Acta Chirurgica Belgica, Vol. 103 (6), 2003)

"It is a monograph composed by urologists … all expert in the field of localised prostate cancer. Hence all essential diagnostic and staging procedures are excellently described and discussed. … This is a really attractive and essential book for all urologists who are learning or already perform radical prostatectomy. … The videos on the CD-ROM are really instructive and more than complementary to the book. Therefore this monograph is ‘a must!’" (European Urology Today, Vol. 14 (2), 2003)

• Department of Urology and Pediatric Urology, Philipps Universität Marburg, Marburg/Lahn, Germany

  Reiner Hofmann, Axel Heidenreich

• Department of Surgery, USUHS, Bethesda, USA

  Judd W. Moul

Policies and ethics