Biliary Tract and Gallbladder Cancer

1. Front Matter

   Pages i-xvii

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2. Epidemiology of Cholangiocarcinoma and Gallbladder Carcinoma

   • Ijeoma A. Azodo, Rowan W. Parks, O. James Garden

   Pages 1-31

3. Role of Growth Factor Signaling Pathways in Biliary Tract Cancer

   • Kaoru Kiguchi, John DiGiovanni

   Pages 33-44

4. Pathology of Gallbladder Cancer

   • Vikram Deshpande, Andrea Primiani

   Pages 45-56

5. Histopathology and Molecular Pathogenesis of Cholangiocarcinoma

   • Laura Rubbia-Brandt, Benoit Terris

   Pages 57-65

6. Novel Biomarkers for Cholangiocarcinoma

   • Ross C. Smith

   Pages 67-82

7. Pathologic Staging

   • Taofic Mounajjed, Tsung-Teh Wu

   Pages 83-98

8. Molecular Profiling

   • Domenico Alvaro, Vincenzo Cardinale

   Pages 99-115

9. Overview of Current Strategies for Diagnostic Imaging of Biliary Tract and Gallbladder Tumors

   • Heljä Oikarinen

   Pages 117-131

10. Imaging of Hilar Cholangiocarcinoma for Liver Transplantation

    • Victor M. Zaydfudim, David M. Nagorney, Charles B. Rosen

    Pages 133-143

11. Magnetic Resonance Imaging (Including MR Cholangiopancreatography)

    • Susanne Bonekamp, Celia Pamela Corona-Villalobos, Vivek Gowdra Halappa, Ihab R. Kamel

    Pages 145-158

12. Functional Imaging

    • Muhammad A. Chaudhry, Lujaien Al-Rubaiey Kadhim, Richard L. Wahl

    Pages 159-166

13. Computed Tomography

    • Gory Ballester-Ortiz, Leonardo Marcal, Chitra Viswanathan, Janio Szklaruk

    Pages 167-200

14. Interventional Radiology Management of Unresectable Intrahepatic Cholangiocarcinoma

    • Adam D. Talenfeld, Daniel J. Holzwanger, David C. Madoff

    Pages 201-223

15. Overview of Emerging Strategies in the Surgical Management of Biliary Tract Tumors

    • Felipe José Fernández Coimbra, Héber Salvador de Castro Ribeiro, Igor Correia de Farias, André Luis de Godoy, Wilson Luiz da Costa Junior

    Pages 225-239

16. Surgical Management of Intra-Hepatic Cholangiocarcinoma

    • Kimberly M. Brown, David A. Geller

    Pages 241-252

17. Surgical Techniques for Extrahepatic Biliary Tract Cancers

    • Junichi Shindoh, Giuseppe Zimmitti, Jean-Nicolas Vauthey

    Pages 253-263

18. Surgical Management of Gallbladder Cancer

    • Amudhan Pugalenthi, Yuman Fong

    Pages 265-274

19. Systemic Therapy: Current Strategies and New Directions

    • Melanie B. Thomas

    Pages 275-281

20. External Beam Radiation Therapy: 3D-Conformal, Intensity-Modulated, and Proton Beam

    • Anusha Kalbasi, Edgar Ben-Josef

    Pages 283-293

The second edition of this book is intended as a definitive text on biliary tract and gallbladder cancers. Specifically, it will serve as a single-source reference on the current knowledge base for the multidisciplinary management of such cancers and thus covers epidemiological, surgical, radiotherapy, and chemotherapy approaches. A key feature is the demonstration of the impact of cutting-edge technical knowledge on treatment; for example, interventional radiology techniques, novel surgical approaches, and image-guided radiation therapy are all extensively discussed. Diagnosis is also considered in detail, with coverage of novel serum biomarkers, pathologic staging, molecular profiling, and the full range of current and emerging imaging strategies. This book will be an invaluable source of information on new techniques for experienced practitioners, yet is sufficiently concise to offer an introduction to the field for students and community practitioners.

• Bile Duct cancer
• Cholangiocarcinoma
• Gallbladder Cancer
• Intrahepatic Cholangiocarcinoma
• Radiation Therapy
• Surgical Oncology
• Radiaton Oncology

• Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, USA

  Joseph M. Herman

• Department of Surgery, Johns Hopkins Hospital, Baltimore, USA

  Timothy M. Pawlik

• Department of Radiation Oncology, Oregon Health and Science University, Portland, USA

  Charles R. Thomas, Jr.

Policies and ethics