Rare Lymphomas

1. Front Matter

   Pages i-x

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2. General

   1. Front Matter

      Pages 1-1

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   2. Principles of the Pathology and Biology of Malignant Lymphomas

      • German Ott, Eric D. Hsi, Jan Delabie, Scott Rodig

      Pages 3-16

   3. Cytogenetics

      • Gordana Raca, Jo-Anne van der Krogt, Michelle M. Le Beau, Iwona Wlodarska

      Pages 17-60

   4. Molecular Genetics of Rare Lymphomas

      • Sören-Sebastian Wenzel, Georg Lenz

      Pages 61-69

   5. Signaling Pathways in Rare Lymphomas

      • Andrew Lipsky, Patricia Pérez-Galán, Claudio Agostinelli, Pier Paolo Piccaluga, Stefano A. Pileri, Adrian Wiestner

      Pages 71-95

3. Disease-Specific: T-NHL

   1. Front Matter

      Pages 97-97

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   2. Adult T-cell Leukemia-Lymphoma

      • Kunihiro Tsukasaki, Kensei Tobinai

      Pages 99-110

   3. Anaplastic Large Cell Lymphoma

      • Anas Younes, Pier Luigi Zinzani, Scott Rodig, Jan Delabie

      Pages 111-120

   4. Extranodal NK/T-Cell Lymphoma, Nasal Type

      • Won Seog Kim, Seok Jin Kim, Young Hyeh Ko

      Pages 121-131

   5. Cutaneous T-Cell Lymphoma

      • Jasmine Zain, Michael Weichenthal, Scott Rodig, Jan Delabie

      Pages 133-167

4. Disease-Specific: B-NHL

   1. Front Matter

      Pages 169-169

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   2. Adult Burkitt Lymphoma and Leukemia

      • Nicola Gökbuget, Paul Barr, Jonathan W. Friedberg, Eric D. Hsi, German Ott

      Pages 171-194

   3. Primary Mediastinal Large B-Cell Lymphoma

      • Peter Johnson, Jan Delabie, Scott Rodig, Maurizio Martelli

      Pages 195-206

   4. CNS Lymphoma

      • Agnieszka Korfel, James Rubenstein, German Ott, Eric D. Hsi

      Pages 207-223

   5. HIV-Associated Lymphomas

      • Kieron Dunleavy, German Ott, Eric D. Hsi, Michele Spina

      Pages 225-240

   6. Non-MALT Marginal Zone Lymphoma

      • Catherine Thieblemont, Steven Bernstein, Scott Rodig, Jan Delabie

      Pages 241-251

   7. Mucosal-Associated Lymphoid Tissue (MALT) Lymphoma

      • Caron A. Jacobson, Luca Arcaini, Ann S. LaCasce, Jan Delabie, Scott Rodig

      Pages 253-276

   8. Mantle Cell Lymphoma

      • Michael E. Williams, L. Kyle Brett, Martin Dreyling, German Ott, Eric D. Hsi

      Pages 277-302

   9. Waldenström’s Macroglobulinemia

      • Véronique Leblond, Giampaolo Merlini, Steven P. Treon, Scott Rodig, Jan Delabie

      Pages 303-329

After a decade of tremendous progress in the diagnostic and therapeutic approaches to malignant lymphoma, optimal treatment strategies are now based not only on accurate diagnosis but also on thorough evaluation of clinical and molecular risk factors. Even more importantly, molecular targeted approaches have been shown to be effective in the treatment of distinct lymphoma subtypes. Against this background, clinical management of especially the rare lymphomas remains a challenge for the general oncologist. This book provides a comprehensive overview of current treatment strategies in these rare lymphoma subtypes. Experts in the field from around the world describe histomorphology in a clinically relevant manner, consider the role of risk factors in detail, and discuss the spectrum of therapeutic approaches. Special emphasis is placed on the translation of molecular science into clinical care, and a disease-specific algorithm is proposed for each entity.

• Malignant Lymphoma
• Molecular Pathogenesis
• Targeted Approaches

From the book reviews:

“Devoted to the rare or unusual subtypes of non-Hodgkin’s lymphoma (NHL), this book provides a comprehensive review of each subtype, including its natural history, pathogenesis, molecular biology, prognosis, management, and future directions. … The intended audience includes hematologists, oncologists, pathologists, established researchers, medical students, and residents, but the book is probably most useful for hematologists, oncologists, and pathologists. … It is a keeper, especially for those interested in lymphoma.” (Auayporn Nademanee, Doody’s Book Reviews, August, 2014)

• Medizinischen Klinik und Poliklinik III, Universität München Klinikum Großhadern, München, Germany

  Martin Dreyling

• Division of Hematology/Oncology and Cancer Center, University of Virginia Health System, Charlottesville, USA

  Michael E. Williams

Policies and ethics