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  • © 2013

CRISPR-Cas Systems

RNA-mediated Adaptive Immunity in Bacteria and Archaea

  • This is the first book in this exciting field
  • Includes the new CRISPR-Cas systems categorization
  • Written by the leading experts of the CRISPR research community
  • Includes supplementary material: sn.pub/extras

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eBook USD 169.00
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Softcover Book USD 219.99
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  • Dispatched in 3 to 5 business days
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Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-x
  2. Discovery and Seminal Developments in the CRISPR Field

    • Francisco J. M. Mojica, Roger A. Garrett
    Pages 1-31
  3. Occurrence, Diversity of CRISPR-Cas Systems and Genotyping Implications

    • Christine Pourcel, Christine Drevet
    Pages 33-59
  4. Regulation of CRISPR-Based Immune Responses

    • Zihni Arslan, Edze R. Westra, Rolf Wagner, Ãœmit Pul
    Pages 93-113
  5. crRNA Biogenesis

    • Emmanuelle Charpentier, John van der Oost, Malcolm F. White
    Pages 115-144
  6. Distribution and Mechanism of the Type I CRISPR-Cas Systems

    • Raymond H. J. Staals, Stan J. J. Brouns
    Pages 145-169
  7. Type II: Streptococcus thermophilus

    • Marie-Ève Dupuis, Sylvain Moineau
    Pages 171-200
  8. Type III CRISPR-Cas Systems and the Roles of CRISPR-Cas in Bacterial Virulence

    • Asma Hatoum-Aslan, Kelli L. Palmer, Michael S. Gilmore, Luciano A. Marraffini
    Pages 201-219
  9. CRISPR-Cas Systems to Probe Ecological Diversity and Host–Viral Interactions

    • Nicole L. Held, Lauren M. Childs, Michelle Davison, Joshua S. Weitz, Rachel J. Whitaker, Devaki Bhaya
    Pages 221-250
  10. Roles of CRISPR in Regulation of Physiological Processes

    • Gil Amitai, Rotem Sorek
    Pages 251-266
  11. Applications of the Versatile CRISPR-Cas Systems

    • Philippe Horvath, Giedrius Gasiunas, Virginijus Siksnys, Rodolphe Barrangou
    Pages 267-286
  12. CRISPRs in the Microbial Community Context

    • Jillian F. Banfield
    Pages 287-291
  13. Back Matter

    Pages 293-299

About this book

CRISPR/Cas is a recently described defense system that protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR/Cas systems has been identified in at least half of the available prokaryotic genomes. On-going structural and functional analyses have resulted in a far greater insight into the functions and possible applications of these systems, although many secrets remain to be discovered.

In this book, experts summarize the state of the art in this exciting field.

Editors and Affiliations

  • DuPont Nutrition and Health, Madison, USA

    Rodolphe Barrangou

  • , Laboratory of Microbiology, University of Wageningen, Wageningen, Netherlands

    John van der Oost

Bibliographic Information

  • Book Title: CRISPR-Cas Systems

  • Book Subtitle: RNA-mediated Adaptive Immunity in Bacteria and Archaea

  • Editors: Rodolphe Barrangou, John van der Oost

  • DOI: https://doi.org/10.1007/978-3-642-34657-6

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2013

  • Hardcover ISBN: 978-3-642-34656-9Published: 14 December 2012

  • Softcover ISBN: 978-3-642-42929-3Published: 29 January 2015

  • eBook ISBN: 978-3-642-34657-6Published: 13 December 2012

  • Edition Number: 1

  • Number of Pages: X, 302

  • Topics: Microbiology, Microbial Genetics and Genomics, Medical Microbiology

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access