Annual Update in Intensive Care and Emergency Medicine 2012

1. Front Matter

   Pages I-XXVII

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2. Mechanisms of Sepsis and Critical Illness

   1. Front Matter

      Pages 1-1

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   2. Molecular Mechanisms Underlying Severe Sepsis: Insights from Epigenetics

      • W. F. Carson IV, S. L. Kunkel

      Pages 3-11

   3. The Neuroendocrine Axis: The Nervous System and Inflammation

      • K. Weismüller, M. A. Weigand, S. Hofer

      Pages 12-18

   4. The mHLA-DR System in the Critically Ill

      • A. Gouel, A. Lepape, B. Allaouchiche

      Pages 19-28

   5. Gut Microbiome and Host Defense Interactions during Critical Illness

      • T. J. Schuijt, T. van der Poll, W. J. Wiersinga

      Pages 29-40

3. Metabolomics

   1. Front Matter

      Pages 41-41

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   2. The Metabolomic Approach to the Diagnosis of Critical Illness

      • N. Nin, J. L. Izquierdo-García, J. A. Lorente

      Pages 43-52

   3. Metabolomics in Critically ill Patients: Focus on Exhaled Air

      • L. D. J. Bos, P. J. Sterk, M. J. Schultz

      Pages 53-62

4. Sepsis Management

   1. Front Matter

      Pages 63-63

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   2. Cardiovascular Effects of Norepinephrine in Septic Shock

      • X. Monnet, J.-L. Teboul

      Pages 65-75

   3. Vasopressin Therapy in Septic Shock

      • S. Rehberg, M. Westphal, C. Ertmer

      Pages 76-84

   4. Antimicrobial Peptides and their Potential Application in Inflammation and Sepsis

      • T. Schuerholz, K. Brandenburg, G. Marx

      Pages 85-97

   5. Hypogammaglobulinemia in Sepsis

      • M. Päsler, S. Dietz, K. Werdan

      Pages 98-108

   6. Timing IgM Treatment in Sepsis: Is Procalcitonin the Answer?

      • Z. Molnár, J. Fogas

      Pages 109-115

   7. Sepsis Stewardship Programs: Methods and Results

      • M. Girardis, S. Busani, A. Pan

      Pages 116-124

5. Endocrine Support

   1. Front Matter

      Pages 125-125

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   2. The Corticotrophin Test in Critical Illness: Traps and Tricks

      • B. Venkatesh, J. Cohen

      Pages 127-137

   3. Glitazones: Could They Have a Rosy Future in Critical Care?

      • S. K. M. Marment, A. J. Semark, P. S. Kruger

      Pages 138-146

6. Acute Respiratory Distress Syndrome

   1. Front Matter

      Pages 147-147

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The Yearbook compiles the most recent developments in experimental and clinical research and practice in one comprehensive reference book. The chapters are written by well recognized experts in the field of intensive care and emergency medicine. It is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.

• Emergency Medicine
• Hemodynamic Monitoring
• Intensive Care Unit
• Respiratory Failure
• Sepsis

From the reviews:

“This is the latest in a series of works summarizing clinical developments and research in critical care and emergency medicine. … Senior trainees in any critical discipline and practitioners are the intended audience for this work, which originates from an international group of authors and is edited by a leader in multidisciplinary critical care. … The topics it covers will be of benefit to practicing intensivists and academicians. … this is a good summary of applied research in the field.” (David J. Dries, Doody’s Review Service, October, 2012)

• Department of Intensive Care Erasme Hospital, Université libre de Bruxelles, Brussels, Belgium

  Jean-Louis Vincent

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