Intradermal Immunization

1. Front Matter

   Pages i-x

   PDF

2. Understanding the Murine Cutaneous Dendritic Cell Network to Improve Intradermal Vaccination Strategies

   • F. Ginhoux, L. G. Ng, M. Merad

   Pages 1-24

3. Insight into the Immunobiology of Human Skin and Functional Specialization of Skin Dendritic Cell Subsets to Innovate Intradermal Vaccination Design

   • M. B. M. Teunissen, M. Haniffa, M. P. Collin

   Pages 25-76

4. Delivery Systems for Intradermal Vaccination

   • Y. C. Kim, C. Jarrahian, D. Zehrung, S. Mitragotri, M. R. Prausnitz

   Pages 77-112

5. Targeting Skin Dendritic Cells to Improve Intradermal Vaccination

   • N. Romani, V. Flacher, C. H. Tripp, F. Sparber, S. Ebner, P. Stoitzner

   Pages 113-138

6. Intradermal Rabies Vaccination: The Evolution and Future of Pre- and Post-exposure Prophylaxis

   • M. J. Warrell

   Pages 139-157

7. Intradermal Vaccination to Protect Against Yellow Fever and Influenza

   • A. H. E. Roukens, L. B. S. Gelinck, L. G. Visser

   Pages 159-179

8. The Dermis as a Portal for Dendritic Cell-Targeted Immunotherapy of Cutaneous Melanoma

   • D. Oosterhoff, B. J. R. Sluijter, B. N. Hangalapura, T. D. de Gruijl

   Pages 181-220

9. DNA Vaccines and Intradermal Vaccination by DNA Tattooing

   • K. Oosterhuis, J. H. van den Berg, T. N. Schumacher, J. B. A. G. Haanen

   Pages 221-250

10. Back Matter

    Pages 251-253

    PDF

This volume of Current Topics in Microbiology and Immunology covers diverse topics related to intradermal immunization. The  chapters highlight the effectiveness of intradermal immunization in experimental animal models or in clinical practice, all supporting the view that intradermal immunization is at least as good as other immunization routes. Keeping in mind that current vaccines are not specially designed for intradermal immunization, but show comparable efficiency even at reduced dosages, this underlines the great potential for the skin as a vaccination site. Hopefully, the overview in this volume will encourage vaccine designers to focus on this promising immunization route, and in addition, to inspire them to develop vaccines that are especially optimized for intradermal immunization.

• DNA tattooing
• Rabies vaccination
• human epidermal Langerhans cells
• influenza vaccination
• intradermal Rabies vaccination
• intradermal immunization
• skin dendritic cells
• yellow fever vaccination
• vaccines

• , Department of Dermatology, University of Amsterdam, Academic Medica, Amsterdam, Netherlands

  Marcel B.M. Teunissen

Policies and ethics