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  • © 2012

Disorders of Sex Development

An Integrated Approach to Management

  • Reports the combined experience of a leading dedicated unit in delivering expert medical and surgical care to children with disorders of sexual development in a holistic environment

  • Documents the most recent advances in the molecular biology and embryology of sex development

  • Describes clinical presentation, diagnosis, and treatment

  • Reports short-, medium-, and long-term outcomes using the holistic approach

  • Includes supplementary material: sn.pub/extras

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Table of contents (27 chapters)

  1. Front Matter

    Pages i-xv
  2. Embryology of the Human Genital Tract

    • John M. Hutson
    Pages 11-21
  3. The Hormones Regulating Sex Development

    • John M. Hutson
    Pages 23-29
  4. Abnormal Embryology in DSD

    • John M. Hutson
    Pages 41-52
  5. 46,XX Disorders of Sex Development

    • Garry L. Warne, Jacqueline K. Hewitt
    Pages 53-61
  6. 46,XY DSD

    • Jacqueline K. Hewitt, Garry L. Warne
    Pages 63-80
  7. Mixed Sex Chromosome and Ovo-Testicular DSD

    • Jacqueline K. Hewitt, Garry L. Warne
    Pages 81-87
  8. Non-hormonal DSD

    • John M. Hutson
    Pages 89-96
  9. Multiple Malformation Syndromes in DSD

    • John M. Hutson
    Pages 97-101
  10. The Neonate with Ambiguous Genitalia

    • John M. Hutson
    Pages 103-114
  11. DSD Later in Childhood

    • John M. Hutson, Garry L. Warne
    Pages 115-124
  12. The Adolescent or Young Adult with DSD

    • John M. Hutson, Garry L. Warne, Sonia R. Grover
    Pages 125-131
  13. Imaging in DSD

    • Murray Bartlett
    Pages 133-145
  14. The Medical Management of Disorders of Sex Development

    • Garry L. Warne, Jacqueline K. Hewitt
    Pages 159-172
  15. Surgical Treatment in Infancy

    • John M. Hutson
    Pages 173-181
  16. Laparoscopy for DSD

    • John M. Hutson, Chris Kimber
    Pages 183-191
  17. The Family

    • Elizabeth Loughlin
    Pages 193-201

About this book

The rapid advances in medicine over the last 50 years have totally changed the outlook for children with disorders of sex development (DSD), but there is still much to learn. This book crystallizes the combined experience of a leading dedicated unit over 25 years in delivering expert medical and surgical care to children with DSD in a holistic environment. It documents the most recent advances in the molecular biology and embryology of sex development, and describes each disorder in detail. The clinical presentation and approach to diagnosis are described both for babies and for children presenting later in childhood or at adolescence. The chapters on management highlight all the latest knowledge and include the shared wisdom of the authors on current controversies, such as the timing of surgical treatment. Finally, the authors describe their short-, medium-, and long-term outcomes, which demonstrate the strengths of holistic team management.

Editors and Affiliations

  • , Department of Urology, The Royal Children's Hospital, Parkville, Australia

    John M. Hutson

  • , Department of Endocrinology and Diabetes, The Royal Children's Hospital, Parkville, Australia

    Garry L. Warne

  • , Department of Gynaecology, Royal Children's Hospital, Parkville, Australia

    Sonia R. Grover

Bibliographic Information

  • Book Title: Disorders of Sex Development

  • Book Subtitle: An Integrated Approach to Management

  • Editors: John M. Hutson, Garry L. Warne, Sonia R. Grover

  • DOI: https://doi.org/10.1007/978-3-642-22964-0

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2012

  • Softcover ISBN: 978-3-662-52045-1Published: 01 October 2016

  • eBook ISBN: 978-3-642-22964-0Published: 14 January 2012

  • Edition Number: 1

  • Number of Pages: XV, 311

  • Number of Illustrations: 81 b/w illustrations, 57 illustrations in colour

  • Topics: Pediatrics, Human Genetics

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access