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Dupuytren’s Disease and Related Hyperproliferative Disorders

Principles, Research, and Clinical Perspectives

  • Book
  • © 2012

Overview

Editors:
  1. Charles Eaton

    1. The Hand Center, Jupiter, USA

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  2. M. Heinrich Seegenschmiedt

    1. Strahlenzentrum Hamburg, Hamburg, Germany

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  3. Ardeshir Bayat

    1. Manchester Interdisciplinary Biocentre, Plastic & Reconstructive Surgery, University of Manchester, Manchester, United Kingdom

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  4. Giulio Gabbiani

    1. Faculty of Medicine, Dept. of Pathology and Immunology, University of Geneva, Geneva, Switzerland

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  5. Paul Werker

    1. Medical Center, Department of Plastic Surgery, University of Groningen, Groningen, Netherlands

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  6. Wolfgang Wach

    1. Dupuytren e.V., Übersee, Germany

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  • Based on presentations at the first symposium for 40 years to be devoted to Dupuytren’s disease
  • Provides up-to-date information on the epidemiology, biology, and pathology of the disease
  • Examines the indications for and techniques of radiotherapy, minimally invasive treatment, and open surgery
  • Considers the role of non-medical treatment and describes the appropriate care of relapse and complications

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Table of contents (54 chapters)

  1. Front Matter

    Pages i-xxiii
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  3. The Myofibroblast

    1. Front Matter

      Pages 51-51
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    2. The Role of the Myofibroblast in Dupuytren’s Disease: Fundamental Aspects of Contraction and Therapeutic Perspectives

      • Boris Hinz, Giulio Gabbiani
      Pages 53-60

    3. Mechanisms of Myofibroblast Differentiation

      • Sem H. Phan
      Pages 61-67

    4. Myofibroblasts and Interactions with Other Cells: Contribution of the Tissue Engineering

      • Véronique Moulin, Judith Bellemare, Daniele Bergeron, Herve Genest, Michel Roy, Carlos Lopez-Vallé
      Pages 69-75

    5. Dupuytren’s Contracture Versus Burn Scar Contracture

      • Paul Zidel
      Pages 77-83

  4. Genetics and Demographics

    1. Front Matter

      Pages 85-85
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    2. The Genetic Basis of Dupuytren’s Disease: An Introduction

      • Guido H. C. G. Dolmans, Hans C. Hennies
      Pages 87-91

    3. Use of Genetic and Genomic Analyses Tools to Study Dupuytren’s Disease

      • Barbara Shih, Stewart Watson, Ardeshir Bayat
      Pages 93-100

    4. Establishing an Animal Model of Dupuytren’s Contracture by Profiling Genes Associated with Fibrosis

      • Latha Satish, Mark E. Baratz, Bradley Palmer, Sandra Johnson, J. Christopher Post, Garth D. Ehrlich et al.
      Pages 101-108

    5. Microarray Expression Analysis of Primary Dupuytren’s Contracture Cells

      • Sandra Kraljevic Pavelic, Ivana Ratkaj
      Pages 109-113

    6. A Clinical Genetic Study of Familial Dupuytren’s Disease in the Netherlands

      • Guido H. C. G. Dolmans, Cisca Wijmenga, Roel Ophoff, Paul M. N. Werker
      Pages 115-122

    7. The Epidemiology of Dupuytren’s Disease in Bosnia

      • Dragan Zerajic, Vilhjalmur Finsen
      Pages 123-127
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Keywords

About this book

This book is based on results of the 2010 International Symposium on Dupuytren's disease held in Miami, Florida, but it also includes new data and additional chapters. It is hoped that it will raise awareness of this underestimated condition and promote cooperative efforts to work towards a cure. Up to date information is provided on the epidemiology, biology, and pathology of the disease. The principles and specifics of treatment are explored in detail. The indications for and techniques of radiotherapy, minimally invasive treatments and open surgery are fully explained. The role of physical therapy is considered as well as the care of relapse and complications. The treatment of Ledderhose’s disease and Peyronie’s disease is also discussed. This book provides invaluable information for hand surgeons, podiatrists, orthopedists, radiation therapy specialists and general practitioners. It will help to foster an interdisciplinary approach to the understanding and management of this debilitating disorder.

Editors and Affiliations

  • The Hand Center, Jupiter, USA

    Charles Eaton

  • Strahlenzentrum Hamburg, Hamburg, Germany

    M. Heinrich Seegenschmiedt

  • Manchester Interdisciplinary Biocentre, Plastic & Reconstructive Surgery, University of Manchester, Manchester, United Kingdom

    Ardeshir Bayat

  • Faculty of Medicine, Dept. of Pathology and Immunology, University of Geneva, Geneva, Switzerland

    Giulio Gabbiani

  • Medical Center, Department of Plastic Surgery, University of Groningen, Groningen, Netherlands

    Paul Werker

  • Dupuytren e.V., Übersee, Germany

    Wolfgang Wach

Bibliographic Information

  • Book Title: Dupuytren’s Disease and Related Hyperproliferative Disorders

  • Book Subtitle: Principles, Research, and Clinical Perspectives

  • Editors: Charles Eaton, M. Heinrich Seegenschmiedt, Ardeshir Bayat, Giulio Gabbiani, Paul Werker, Wolfgang Wach

  • DOI: https://doi.org/10.1007/978-3-642-22697-7

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2012

  • Hardcover ISBN: 978-3-642-22696-0Published: 19 January 2012

  • Softcover ISBN: 978-3-662-50611-0Published: 23 August 2016

  • eBook ISBN: 978-3-642-22697-7Published: 22 December 2011

  • Edition Number: 1

  • Number of Pages: XXIII, 474

  • Number of Illustrations: 55 b/w illustrations, 198 illustrations in colour

  • Topics: Orthopedics, Surgical Orthopedics, General Practice / Family Medicine, Dermatology

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