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  • © 2011

Behavioral Neurobiology of Bipolar Disorder and its Treatment

  • Covers a wide range of methodologies including neuroimaging, genetics and epigenetics, animal models, translational research and psychopharmacology
  • Describes the most effective currently available treatments for the disorder as well as potential novel therapeutics
  • Brings together a group of widely-respected investigators in various fields to provide the reader with the most specific and up-to-date findings
  • Includes supplementary material: sn.pub/extras

Part of the book series: Current Topics in Behavioral Neurosciences (CTBN, volume 5)

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Table of contents (18 chapters)

  1. Front Matter

    Pages i-xvi
  2. Course and Outcome of Bipolar Disorder

    • Philip B. Mitchell, Dusan Hadzi-Pavlovic, Colleen K. Loo
    Pages 1-18
  3. Genetics of Bipolar Disorder

    • Jens R. Wendland, Francis J. McMahon
    Pages 19-30
  4. Understanding Bipolar Disorder: The Epigenetic Perspective

    • Tarang Khare, Mrinal Pal, Arturas Petronis
    Pages 31-49
  5. Clinical Endophenotypes for Bipolar Disorder

    • David C. Glahn, Katherine E. Burdick
    Pages 51-67
  6. Partial Rodent Genetic Models for Bipolar Disorder

    • Guang Chen, Ioline D. Henter, Husseini K. Manji
    Pages 89-106
  7. The Role of the Aminergic Systems in the Pathophysiology of Bipolar Disorder

    • Espen Walderhaug, Monica Varga, Michelle San Pedro, Jian Hu, Alexander Neumeister
    Pages 107-126
  8. Signal Transduction Pathways in the Pathophysiology of Bipolar Disorder

    • Jeremy W. Gawryluk, L. Trevor Young
    Pages 139-165
  9. Synaptic Plasticity in the Pathophysiology and Treatment of Bipolar Disorder

    • Jing Du, Rodrigo Machado-Vieira, Rushaniya Khairova
    Pages 167-185
  10. Neuroimaging and Neuropathological Findings in Bipolar Disorder

    • Jonathan Savitz, Wayne C. Drevets
    Pages 201-225
  11. Functional Neuroimaging Research in Bipolar Disorder

    • Benjamin N. Blond, Hilary P. Blumberg
    Pages 227-245
  12. Nonpharmacotherapeutic Somatic Treatments for Bipolar Disorder (ECT, DBS, rTMS)

    • Colleen Loo, Benjamin Greenberg, Philip Mitchell
    Pages 285-302
  13. Potential Novel Therapeutics for Bipolar Disorders

    • Rodrigo Machado-Vieira, Husseini K. Manji, Carlos A. Zarate Jr.
    Pages 303-329
  14. Bipolar Disorder: A Neurobiological Synthesis

    • Husseini K. Manji, Ioline D. Henter, Carlos A. Zarate Jr.
    Pages 331-340
  15. Back Matter

    Pages 341-347

About this book

This book offers the most up-to-date information about research surrounding the neurobiology of bipolar disorder as well as currently available and novel therapeutic options. The volume has assembled a widely respected group of preclinical and clinical researchers who bring their expertise to bear upon this illness by reviewing cutting-edge research and clinical evidence regarding the pathophysiology and treatment of bipolar disorder. Early chapters review the course and outcome and genetics of this highly heritable condition, including chapters on epigenetics and clinical endophenotypes. Several chapters offer a remarkably thorough and unique overview of the neurobiology of the disorder, including what is known from neuroimaging work and the development of animal models. Finally, the book covers treatment strategies for bipolar disorder, including both traditional and novel therapeutics, as well as non-pharmacological treatments. It offers both researchers and clinicians key insights into this devastating disorder.

Editors and Affiliations

  • Research & Development, LLC, Johnson & Johnson Pharmaceutical, Titusville, USA

    Husseini K. Manji

  • Mark O. Hatfield Clinical Res. Center, Lab. of Molecular Pathophysiology, National Institute of Mental Health, Bethesda, USA

    Carlos A. Zarate Jr.

Bibliographic Information

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access