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  • © 2010

Medicinal Organometallic Chemistry

  • Each volume of Topics in Organometallic Chemistry provides the broad scientific readership with a comprehensive summary and critical overview of a specific topic in organometallic chemistry
  • Research in this rapidly developing transdisciplinary field is having profound influence on other areas of scientific investigation, ranging from catalytic organic synthesis to biology, medicine and material science
  • With contributions by international experts
  • Includes supplementary material: sn.pub/extras

Part of the book series: Topics in Organometallic Chemistry (TOPORGAN, volume 32)

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-xviii
  2. Activation Mechanisms for Organometallic Anticancer Complexes

    • Ana M. Pizarro, Abraha Habtemariam, Peter J. Sadler
    Pages 21-56
  3. Organometallic Antitumour Agents with Alternative Modes of Action

    • Angela Casini, Christian G. Hartinger, Alexey A. Nazarov, Paul J. Dyson
    Pages 57-80
  4. Ferrocene Functionalized Endocrine Modulators as Anticancer Agents

    • Elizabeth A. Hillard, Anne Vessières, Gerard Jaouen
    Pages 81-117
  5. Organometallics as Structural Scaffolds for Enzyme Inhibitor Design

    • Seann P. Mulcahy, Eric Meggers
    Pages 141-153
  6. Bioorganometallic Chemistry and Malaria

    • Christophe Biot, Daniel Dive
    Pages 155-193
  7. Organometallic Radiopharmaceuticals

    • Roger Alberto
    Pages 219-246
  8. Back Matter

    Pages 287-291

About this book

Contents: Gérard Jaouen, Nils Metzler-Nolte : Introduction ; Stéphane GIBAUD and Gérard JAOUEN: Arsenic - based drugs: from Fowler’s solution to modern anticancer chemotherapy; Ana M. Pizarro, Abraha Habtemariam and Peter J. Sadler : Activation Mechanisms for Organometallic Anticancer Complexes; Angela Casini, Christian G. Hartinger, Alexey A. Nazarov, Paul J. Dyson : Organometallic antitumour agents with alternative modes of action; Elizabeth A. Hillard, Anne Vessières, Gerard Jaouen : Ferrocene functionalized endocrine modulators for the treatment of cancer; Megan Hogan and Matthias Tacke : Titanocenes – Cytotoxic and Anti-Angiogenic Chemotherapy Against Advanced Renal-Cell Cancer; Seann P. Mulcahy and Eric Meggers : Organometallics as Structural Scaffolds for Enzyme Inhibitor Design; Christophe Biot and Daniel Dive : Bioorganometallic Chemistry and Malaria; Nils Metzler-Nolte : Biomedical applications of organometal-peptide conjugates; Roger Alberto : Organometallic Radiopharmaceuticals; Brian E. Mann : Carbon Monoxide – an essential signaling molecule.

Reviews

From the reviews:

“Edited by Gèrard Jaouen and Nils Metzler-Nolte, this book describes recent advances in the design, synthesis, mechanistic understanding and medical application of organometallic compounds. … Overall this is an informative book and will be welcomed by those working in the field of inorganic medicinal chemistry.” (Simon P. Fricker, Platinum Metals Reviews, Vol. 55 (4), October, 2011)

Editors and Affiliations

  • Chimie de Paris (ENSCP), Ecole Nationale Superieure de, Paris CX 05, France

    Gérard Jaouen

  • LS für Anorganische Chemie I -, Bioanorganische Chemie, Universität Bochum, Bochum, Germany

    Nils Metzler-Nolte

Bibliographic Information

Buy it now

Buying options

eBook USD 259.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 329.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access